Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359263 | 0.91 | MAPT (0.65) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL13959568 | 0.84 | LMNA (0.71) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL21991843 | 0.84 | TSHR (0.67) | HPGDL3MBTL1ALDH1A1CYP2C9MEN1 | |
| SCHEMBL7827993 | 0.81 | TSHR (0.71) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL12900938 | 0.80 | MAPT (0.56) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL11196941 | 0.80 | KMT2A (0.59) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL13861973 | 0.77 | L3MBTL1 (0.75) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL18122081 | 0.77 | MAPT (0.65) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL10358917 | 0.77 | MAPT (0.65) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL19607315 | 0.76 | L3MBTL1 (0.64) | MAPTCYP2C19HPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410396-A | Chromane derivatives | RAQUALIA PHARMA INC (JP) | 2009-04-15 | — | — | CN | disclosed |
| EP-1996589-A1 | CHROMANE DERIVATIVES | RaQualia Pharma Inc (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107827-A1 | CHROMANE DERIVATIVES | RAQUALIA PHARMA INC. (JP) | 2007-09-27 | — | — | WO | disclosed |
| US-20070219237-A1 | Chromane Derivatives | PFIZER INC | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219237-A1 | Chromane Derivatives | HRH2, HRH1, CHRM1 | MAPT 4857/4885CYP2C19 690/4885HPGD 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.