Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655750 | 1.00 | CA12 (0.65) | CA12CA7CA9CA14CA1 | |
| SCHEMBL20857445 | 0.89 | CA12 (0.67) | CA12CA7CA9CA14CA1 | |
| SCHEMBL6335525 | 0.89 | CA12 (0.67) | CA12CA7CA9CA14CA1 | |
| SCHEMBL6340119 | 0.88 | CA12 (0.65) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL112445 | 0.87 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL1866942 | 0.87 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL112446 | 0.87 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL12001792 | 0.87 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| SCHEMBL9643718 | 0.87 | ALOX5 (0.62) | CA12CA7CA9CA14CA1 | |
| SCHEMBL9643721 | 0.87 | ALOX5 (0.62) | CA12CA7CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625207-A4 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | THERACOS INC (US) | 2008-11-12 | — | — | EP | disclosed |
| US-20080188654-A1 | Compounds for treatment of inflammation, diabetes and related disorders | THERACOS, INC. (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080108825-A1 | Compounds for treatment of inflammation, diabetes and related disorders | THERACOS, INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080103302-A1 | Compounds for treatment of inflammation, diabetes and related disorders | THERACOS, INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-7323496-B2 | Compounds for treatment of inflammation, diabetes and related disorders | THERACOS, INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-20070259961-A9 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | NEOGI PARTHA | 2007-11-08 | — | — | US | disclosed |
| EP-1625207-A2 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | Theracos, Inc. (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101752-A2 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | THERACOS, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| EP-1448515-A2 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | Theracos, Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20040097593-A1 | Compounds for treatment of inflammation, diabetes and related disorders | SEED, BRIAN | 2004-05-20 | — | — | US | disclosed |
| WO-2003048108-A2 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | THERACOS, INC (US) | 2003-06-12 | — | — | WO | disclosed |
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259961-A9 | COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS | CPS1, ABAT, IL6 | CA12 1306/4885CA7 645/4885CA9 405/4885 |
| US-20080103302-A1 | Compounds for treatment of inflammation, diabetes and related disorders | CPS1, ABAT, IL6 | CA12 1294/4885CA7 619/4885CA9 399/4885 |
| US-20080108825-A1 | Compounds for treatment of inflammation, diabetes and related disorders | CPS1, ABAT, IL6 | CA12 1294/4885CA7 619/4885CA9 399/4885 |
| US-20040097593-A1 | Compounds for treatment of inflammation, diabetes and related disorders | CPS1, ABAT, IL6 | CA12 1306/4885CA7 645/4885CA9 405/4885 |
| US-20080188654-A1 | Compounds for treatment of inflammation, diabetes and related disorders | CPS1, ABAT, IL6 | CA12 1294/4885CA7 619/4885CA9 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.