Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508622 | 0.98 | LMNA (0.53) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL8413835 | 0.88 | LMNA (0.65) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL8976918 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL29196948 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL1662976 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL2258521 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL2254700 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL344802 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL2253473 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E | |
| SCHEMBL29197325 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1DGKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200433-B1 | NEW ANTIBACTERIAL AGENT BASED ON FATTY ACID ESTERS OF HYDROXY CARBOXYLIC ACIDS | PURAC BIOCHEM BV (NL) | 2011-07-20 | — | — | EP | claimed |