Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655315 | 0.92 | ECE1 (0.48) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL4656220 | 0.90 | ECE1 (0.59) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL4655241 | 0.88 | NOTUM (0.49) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL28788204 | 0.86 | ECE1 (0.48) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL3569792 | 0.86 | PLA2G10 (0.58) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL4656319 | 0.84 | ECE1 (0.50) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL4655331 | 0.84 | MAOB (0.51) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL4655285 | 0.84 | ECE1 (0.53) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL4655419 | 0.84 | CFTR (0.47) | ECE1NOTUMHTR2CMEN1KMT2A | |
| SCHEMBL3571160 | 0.82 | ECE1 (0.48) | ECE1NOTUMHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |