Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | THRB | P10828 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656427 | 0.95 | MAPT (0.69) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4655654 | 0.94 | MAPT (0.72) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Bromide SCHEMBL4655670 | 0.94 | MAPT (0.68) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Hexamethyl Pararosaniline SCHEMBL94116 | 0.80 | TDP1 (0.96) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Hexamethyl Pararosaniline SCHEMBL9171 | 0.79 | TDP1 (1.00) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Perchlorate SCHEMBL4655875 | 0.79 | MAPT (0.76) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Brilliant Green SCHEMBL171205 | 0.78 | TDP1 (0.84) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Perchlorate SCHEMBL4657954 | 0.78 | MAPT (0.74) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Brilliant Green SCHEMBL28216 | 0.76 | TDP1 (0.88) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Perchlorate SCHEMBL4655673 | 0.76 | KMT2A (0.67) | MAPTMEN1KMT2ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435227-B1 | Composition for the dyeing of keratinous fibres comprising a direct dye of the monoheteroyldiarylmethane type or a leuco precursor thereof and a dyeing process using it | OREAL (FR) | 2008-12-03 | — | — | EP | claimed |