Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hexamethyl Pararosaniline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 1.00 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 1.00 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 1.00 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 1.00 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 1.00 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | THRB | P10828 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexamethyl Pararosaniline SCHEMBL94116 | 0.98 | TDP1 (0.96) | TDP1MAPK1MEN1KMT2ATHRB | |
| Brilliant Green SCHEMBL28216 | 0.94 | TDP1 (0.88) | TDP1MAPK1MEN1KMT2ATHRB | |
| SCHEMBL4655638 | 0.92 | MAPT (0.85) | TDP1MAPK1MEN1KMT2ATHRB | |
| SCHEMBL14310873 | 0.92 | TDP1 (0.84) | TDP1MAPK1MEN1KMT2ATHRB | |
| Brilliant Green SCHEMBL171205 | 0.92 | TDP1 (0.84) | TDP1MAPK1MEN1KMT2ATHRB | |
| Hydrochloric Acid SCHEMBL2053249 | 0.91 | TDP1 (0.82) | TDP1MAPK1MEN1KMT2ATHRB | |
| SCHEMBL171347 | 0.90 | MAPK1 (0.82) | TDP1MAPK1MEN1KMT2ATHRB | |
| Hydrochloric Acid SCHEMBL25301058 | 0.89 | TDP1 (0.80) | TDP1MAPK1MEN1KMT2ATHRB | |
| SCHEMBL171207 | 0.89 | TDP1 (0.79) | TDP1MAPK1MEN1KMT2ATHRB | |
| Brilliant Green SCHEMBL29407509 | 0.88 | TDP1 (0.78) | TDP1MAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 117513 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144585-A1 | TIGHTLY TARGETED MINIMALLY INVASIVE (TTMIT) HYPERFUNCTIONING TISSUE ABLATING INSTRUMENT SYSTEM | Schwartz, Alan N. (US) | 2026-05-28 | — | — | US | claimed |
| CN-122081253-A | Laccase mutant and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080543-A | Intelligent cable with temperature control and color change early warning functions and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-117487536-B | Double-shell thermochromic microcapsule as well as preparation method and application thereof | Wuhan Zhongke Advanced Material Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| US-12638442-B2 | Thermo-plasmonic biochip, manufacturing method thereof, biosensing system containing the thermo-plasmonic biochip, and application thereof | RAFAEL BIOTECHNOLOGY COMPANY LIMITED (CN) | 2026-05-26 | — | — | US | claimed |
| US-12636198-B2 | Bandage for providing protection and antimicrobial properties to a surgical site with one or more percutaneous pins or wires | ORTHOBARRIER TECHNOLOGIES LLC (US) | 2026-05-26 | — | — | US | claimed |
| WO-2026102852-A1 | PRESSURE-SENSITIVE MATERIAL, AND PRESSURE-SENSITIVE MATERIAL-BASED METHOD FOR IDENTIFYING INSULATING GAS LEAKAGE | 国网江苏省电力有限公司电力科学研究院 | 2026-05-21 | — | — | WO | claimed |
| CN-117626691-B | Temperature-sensitive color-changing spun-laced non-woven fabric and preparation method thereof | 杭州路先新材料科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060414-A | Electric sensing paint, coating, preparation method, curing method and application | 云南电网有限责任公司电力科学研究院 | 2026-05-19 | — | — | CN | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-4006023-A | Photographic polymeric composition containing a leuco dye cyanide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1977-02-01 | — | — | US | claimed |
| US-4005237-A | Non-bleed pre-printed spirit duplicating masters | THE MAZER CORPORATION (US) | 1977-01-25 | — | — | US | claimed |
| US-3979550-A | Pre-printed latent image spirit duplicating masters | THE MAZER CORPORATION (US) | 1976-09-07 | — | — | US | claimed |
| US-3975158-A | Analysis of gentian violet residue in tissue | A.H.P., INC. (US) | 1976-08-17 | — | — | US | claimed |
| US-3971855-A | Prevention of fungi and molds in poultry and animal feedstuffs with methyl rosaniline chloride additive | NAREMCO, INC. (US) | 1976-07-27 | — | — | US | claimed |
| US-3970459-A | Process for developing a direct reversal silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |
| US-3966414-A | FREE-RADICAL SENSITIVE DYE, PEROXIDE | BIO-MEDICAL SCIENCES, INC. (US) | 1976-06-29 | — | — | US | claimed |
| US-3963510-A | LAKE FORMING ORGANIC DYE, SODIUM WATERGLASS, SODIUM MOLYBDATE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-06-15 | — | — | US | claimed |
| US-3962526-A | Tissueless pre-printed spirit duplicating masters | THE MAZER CORPORATION (US) | 1976-06-08 | — | — | US | claimed |
| US-3962413-A | Plate methods for diagnosing Brucella canis infection | CORNELL RESEARCH FOUNDATION, INC. (US) | 1976-06-08 | — | — | US | claimed |