Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Brilliant Green. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.88 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.88 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.88 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.88 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.88 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.88 |
| ▸ | MEN1 | O00255 | 5/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.88 |
| ▸ | THRB | P10828 | 4/20 | 0.88 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.88 |
| ▸ | MAPT | P10636 | 4/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.88 |
| ▸ | HTT | P42858 | 3/20 | 0.88 |
| ▸ | TP53 | P04637 | 3/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.88 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.88 |
| ▸ | RECQL | P46063 | 2/20 | 0.88 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brilliant Green SCHEMBL171205 | 0.98 | TDP1 (0.84) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Hexamethyl Pararosaniline SCHEMBL9171 | 0.94 | TDP1 (1.00) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Hexamethyl Pararosaniline SCHEMBL94116 | 0.92 | TDP1 (0.96) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Brilliant Green SCHEMBL28515271 | 0.90 | MEN1 (0.90) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Brilliant Green SCHEMBL29379377 | 0.90 | MEN1 (0.85) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Brilliant Green SCHEMBL29616846 | 0.89 | ALDH1A1 (0.97) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Hydrochloric Acid SCHEMBL2053249 | 0.88 | TDP1 (0.82) | TDP1MEN1KMT2ATHRBMAPK1 | |
| Brilliant Green SCHEMBL29365780 | 0.88 | ALDH1A1 (1.00) | TDP1MEN1KMT2ATHRBMAPK1 | |
| SCHEMBL4655638 | 0.86 | MAPT (0.85) | TDP1MEN1KMT2ATHRBMAPK1 | |
| SCHEMBL171207 | 0.86 | TDP1 (0.79) | TDP1MEN1KMT2ATHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 48304 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4749288-A1 | COMPOSITIONS FOR DETECTING, CHARACTERIZING, AND REMOVING A BIOFILM | COSA Group GmbH (DE) | 2026-05-27 | — | — | EP | claimed |
| US-12637709-B2 | Method for detecting SARS-CoV-related betacoronaviruses | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2026-05-26 | — | — | US | claimed |
| CN-122081063-A | Concentration, temperature and illumination multi-factor cell culture chip device and method | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081253-A | Laccase mutant and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-117147651-B | G4-DNA tetrahedral probe electrode, preparation method, application and application method thereof | ZHEJIANG ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-116947055-B | Production method of spherical silica gel for catalyst carrier and spherical silica gel obtained by production method | 青岛美高集团有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122038136-A | Penicillium laccase-producing strain and application thereof | 佛山大学 | 2026-05-15 | — | — | CN | claimed |
| CN-115532237-B | Preparation method of adsorbent for removing malachite green in wastewater | 武汉轻工大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122037910-A | Preparation method of ternary color-changing microcapsule for visualization of local overheating of power equipment | 重庆大学 | 2026-05-15 | — | — | CN | claimed |
| US-4022617-A | DIFFUSION | EASTMAN KODAK COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| US-4013531-A | Method of producing high molecular film containing ionized material | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-03-22 | — | — | US | claimed |
| US-4006023-A | Photographic polymeric composition containing a leuco dye cyanide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1977-02-01 | — | — | US | claimed |
| US-3986880-A | NON-SILVER, LEUCO DYES, PLASTICIZERS, TRIPHENYLCARBINOL, AND ALCOHOLS OR PHENOLS | HORIZONS INCORPORATED A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1976-10-19 | — | — | US | claimed |
| US-3984605-A | Heat sensitive recording material containing decolorizing agent | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-10-05 | — | — | US | claimed |
| US-3981683-A | FOR USE IN AUTOCLAVE | BIO-MEDICAL SCIENCES, INC. (US) | 1976-09-21 | — | — | US | claimed |
| US-RE28956-E | CELLULOSE DERIVATIVES OR ADDITION POLYMERS N-VINYL AMINES, AMIDES OR IMIDES AND HALOGENATED HYDROCARBON, FILMS | HORIZONS RESEARCH INCORPORATED (US) | 1976-09-07 | — | — | US | claimed |
| US-3978429-A | MODE-LOCKED LASER | BELL TELEPHONE LABORATORIES, INCORPORATED (US) | 1976-08-31 | — | — | US | claimed |
| US-3978247-A | IRRADIATION OF BINDERLESS DRY FILM; DYE OR PIGMENT VAPORIZATION | RCA CORPORATION (US) | 1976-08-31 | — | — | US | claimed |
| US-3966414-A | FREE-RADICAL SENSITIVE DYE, PEROXIDE | BIO-MEDICAL SCIENCES, INC. (US) | 1976-06-29 | — | — | US | claimed |