Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657171 | 1.00 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL4657188 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL4657184 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL17513207 | 0.77 | MAPT (0.55) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL19378088 | 0.77 | MAPT (0.55) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL17513208 | 0.77 | MAPT (0.55) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL11194302 | 0.74 | MAPT (0.45) | ALDH1A1SMN1; SMN2MAPTKDM4EMAPK1 | |
| SCHEMBL4991926 | 0.72 | KDM4E (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4EMAPK1 | |
| SCHEMBL4991934 | 0.72 | KDM4E (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4EMAPK1 | |
| SCHEMBL4431736 | 0.72 | KDM4E (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996589-A1 | CHROMANE DERIVATIVES | RaQualia Pharma Inc (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107827-A1 | CHROMANE DERIVATIVES | RAQUALIA PHARMA INC. (JP) | 2007-09-27 | — | — | WO | disclosed |