Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657184 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDNPSR1CYP2C9 | |
| SCHEMBL4657172 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDNPSR1CYP2C9 | |
| SCHEMBL4657171 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDNPSR1CYP2C9 | |
| SCHEMBL15902989 | 0.79 | EPHX2 (0.35) | ALDH1A1MAPTHPGDCYP2C9CYP2C19 | |
| SCHEMBL28440000 | 0.78 | SRC (0.41) | ALDH1A1MAPTHPGDCYP2C9CYP2C19 | |
| SCHEMBL28925118 | 0.78 | KMT2A (0.44) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL18353123 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDCYP2C9CYP2C19 | |
| SCHEMBL13960542 | 0.72 | MAPT (0.38) | ALDH1A1MAPTHPGDNPSR1CYP2C9 | |
| SCHEMBL14926720 | 0.72 | MAPT (0.50) | ALDH1A1MAPTHPGDNPSR1CYP2C9 | |
| SCHEMBL28656820 | 0.71 | TSHR (0.39) | ALDH1A1MAPTHPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996589-A1 | CHROMANE DERIVATIVES | RaQualia Pharma Inc (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107827-A1 | CHROMANE DERIVATIVES | RAQUALIA PHARMA INC. (JP) | 2007-09-27 | — | — | WO | disclosed |
| US-20070219237-A1 | Chromane Derivatives | PFIZER INC | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219237-A1 | Chromane Derivatives | HRH2, HRH1, CHRM1 | ALDH1A1 2284/4885MAPT 4857/4885HPGD 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.