Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921099 | 0.92 | GPR84 (0.48) | GPR84L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL13425464 | 0.86 | ALDH1A1 (0.49) | GPR84L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL13064498 | 0.83 | GPR84 (0.53) | GPR84L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL29586665 | 0.83 | CA12 (0.62) | MAPTALDH1A1HPGDMEN1CYP2C9 | |
| SCHEMBL14127254 | 0.83 | CA12 (0.62) | MAPTALDH1A1HPGDMEN1CYP2C9 | |
| SCHEMBL196970 | 0.83 | CA12 (0.62) | MAPTALDH1A1HPGDMEN1CYP2C9 | |
| SCHEMBL13020438 | 0.82 | GPR84 (0.46) | GPR84L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL21327259 | 0.79 | MAOB (0.58) | GPR84L3MBTL1MAPTALDH1A1ALOX12 | |
| SCHEMBL19555416 | 0.79 | MCL1 (0.67) | L3MBTL1MAPTPOLBCYP2C19TDP1 | |
| Nitrogen SCHEMBL8497790 | 0.78 | CA12 (0.56) | MAPTALDH1A1HPGDMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186609-B1 | Diphosphines | SALTIGO GMBH (DE) | 2008-12-03 | — | — | EP | disclosed |
| US-6844462-B2 | Reacting phenol with an alkali metal hydride, etherification, cyclization, decyclization, hydroxylation, phosphorylation; forming a chemical intermediates for phosphine catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-18 | — | — | US | disclosed |
| US-20030181736-A1 | Diphosphines | LANXESS DEUTSCHLAND GMBH (DE) | 2003-09-25 | — | — | US | disclosed |
| US-6566298-B2 | For use as catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-20030045713-A1 | Diphosphines | LANXESS DEUTSCHLAND GMBH (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6462200-B2 | CONVERTING A PHENOL INTO THE CORRESPONDING PHENOXIDE USING A BASE, REACTING THE PHENOXIDE WITH DIHALOGENOMETHANE TO GIVE A FORMALDEHYDE ACETAL, INTRAMOLECULARLY OXIDATIVELY COUPLING THE FORMALDEHYDE ACETAL TO GIVE A CYCLOHEPTADIENE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-20020055653-A1 | Converting a phenol into the corresponding phenoxide using a base, reacting the phenoxide with dihalogenomethane to give a formaldehyde acetal, intramolecularly oxidatively coupling the formaldehyde acetal to give a cycloheptadiene | LANXESS DEUTSCHLAND GMBH (DE) | 2002-05-09 | — | — | US | disclosed |
| EP-1186609-A2 | Diphosphines | BAYER AG (DE) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045713-A1 | Diphosphines | CBR1, SCO2, CCR1 | GPR84 3419/4885L3MBTL1 500/4885MAPT 4840/4885 |
| US-20020055653-A1 | Converting a phenol into the corresponding phenoxide using a base, reacting the phenoxide with dihalogenomethane to give a formaldehyde acetal, intramolecularly oxidatively coupling the formaldehyde acetal to give a cycloheptadiene | CBR1, PAH, CYP2E1 | GPR84 2860/4885L3MBTL1 1982/4885MAPT 4681/4885 |
| US-20030181736-A1 | Diphosphines | CBR1, SCO2, CCR1 | GPR84 3419/4885L3MBTL1 500/4885MAPT 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.