Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031971 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 | |
| SCHEMBL28999634 | 0.85 | PDE4B (0.55) | ALDH1A1HSD17B10KDM4ETPMTTSHR | |
| SCHEMBL17744214 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 | |
| SCHEMBL11760316 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 | |
| SCHEMBL5992537 | 0.77 | CYP3A4 (0.52) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 | |
| SCHEMBL9332617 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 | |
| SCHEMBL4842699 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KDM4EMAPK1TSHR | |
| SCHEMBL4255276 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 | |
| SCHEMBL10920936 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4ETPMTTSHR | |
| SCHEMBL2094518 | 0.73 | CA1 (0.52) | ALDH1A1HSD17B10KDM4ECYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186609-B1 | Diphosphines | SALTIGO GMBH (DE) | 2008-12-03 | — | — | EP | disclosed |
| US-6844462-B2 | Reacting phenol with an alkali metal hydride, etherification, cyclization, decyclization, hydroxylation, phosphorylation; forming a chemical intermediates for phosphine catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-18 | — | — | US | disclosed |
| US-20030181736-A1 | Diphosphines | LANXESS DEUTSCHLAND GMBH (DE) | 2003-09-25 | — | — | US | disclosed |
| US-6566298-B2 | For use as catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-20030045713-A1 | Diphosphines | LANXESS DEUTSCHLAND GMBH (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6462200-B2 | CONVERTING A PHENOL INTO THE CORRESPONDING PHENOXIDE USING A BASE, REACTING THE PHENOXIDE WITH DIHALOGENOMETHANE TO GIVE A FORMALDEHYDE ACETAL, INTRAMOLECULARLY OXIDATIVELY COUPLING THE FORMALDEHYDE ACETAL TO GIVE A CYCLOHEPTADIENE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-20020055653-A1 | Converting a phenol into the corresponding phenoxide using a base, reacting the phenoxide with dihalogenomethane to give a formaldehyde acetal, intramolecularly oxidatively coupling the formaldehyde acetal to give a cycloheptadiene | LANXESS DEUTSCHLAND GMBH (DE) | 2002-05-09 | — | — | US | disclosed |
| EP-1186609-A2 | Diphosphines | BAYER AG (DE) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045713-A1 | Diphosphines | CBR1, SCO2, CCR1 | ALDH1A1 1203/4885HSD17B10 3636/4885KDM4E 1653/4885 |
| US-20020055653-A1 | Converting a phenol into the corresponding phenoxide using a base, reacting the phenoxide with dihalogenomethane to give a formaldehyde acetal, intramolecularly oxidatively coupling the formaldehyde acetal to give a cycloheptadiene | CBR1, PAH, CYP2E1 | ALDH1A1 83/4885HSD17B10 675/4885KDM4E 785/4885 |
| US-20030181736-A1 | Diphosphines | CBR1, SCO2, CCR1 | ALDH1A1 1203/4885HSD17B10 3636/4885KDM4E 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.