Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848722 | 0.79 | MPL (0.41) | MPLKDM4ESCN9AHCAR1ALOX5AP | |
| SCHEMBL29471353 | 0.79 | HTR7 (0.38) | SCN9APOLBNPSR1CA1CA2 | |
| SCHEMBL615592 | 0.79 | HTR7 (0.38) | SCN9APOLBNPSR1CA1CA2 | |
| SCHEMBL16184453 | 0.78 | MPL (0.44) | MPLKDM4ESCN9AKCNK3KCNK9 | |
| SCHEMBL25310703 | 0.76 | KDM4E (0.34) | MPLKDM4ESCN9AKCNK3KCNK9 | |
| SCHEMBL5733587 | 0.76 | HSD11B1 (0.36) | MPLKDM4ESCN9AHCAR1KCNK3 | |
| SCHEMBL30010792 | 0.76 | MRGPRX4 (0.38) | MPLKDM4ESCN9A | |
| SCHEMBL10874519 | 0.76 | MRGPRX4 (0.38) | MPLKDM4ESCN9A | |
| SCHEMBL10417860 | 0.76 | MPL (0.43) | MPLKDM4ESCN9APOLBGAA | |
| SCHEMBL21603543 | 0.76 | GRIA1 (0.42) | MPLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999096-A2 | PROCESS FOR THE PREPARATION OF 1-BROMO-3-TRIFLUOROMETHOXYBENZENE | MITENI S.p.A. (IT) | 2008-12-10 | — | — | EP | claimed |
| WO-2007107820-A2 | PROCESS FOR THE PREPARATION OF 1-BROMO-3-TRIFLUOROMETHOXYBENZENE | MITENI S.P.A. (IT) | 2007-09-27 | — | — | WO | claimed |
| EP-1999096-A2 | PROCESS FOR THE PREPARATION OF 1-BROMO-3-TRIFLUOROMETHOXYBENZENE | MITENI S.p.A. (IT) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007107820-A2 | PROCESS FOR THE PREPARATION OF 1-BROMO-3-TRIFLUOROMETHOXYBENZENE | MITENI S.P.A. (IT) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107820-A2 | PROCESS FOR THE PREPARATION OF 1-BROMO-3-TRIFLUOROMETHOXYBENZENE | MITENI S.P.A. (IT) | 2007-09-27 | — | — | WO | disclosed |