Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4657846

N.N.Nc1ccc(Oc2cccc(N)c2)cc1

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.79
MAPT P10636 4/20 0.79
SMN1; SMN2 Q16637 3/20 0.79
MEN1 O00255 2/20 0.79
KMT2A Q03164 2/20 0.79
MITF O75030 1/20 0.79
GAA P10253 1/20 0.79
GFER P55789 1/20 0.79
NLRP1 Q9C000 1/20 0.79
NOD2 Q9HC29 1/20 0.79
MAOB P27338 2/20 0.76
MAOA P21397 2/20 0.64
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
NLRP3 Q96P20 1/20 0.62
CYP3A4 P08684 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
TSHR P16473 1/20 0.61
POLB P06746 2/20 0.55
HSP90AA1 P07900 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366093 0.98 ALDH1A1 (0.83) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL15876510 0.98 ALDH1A1 (0.83) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL8432560 0.98 ALDH1A1 (0.83) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL710424 0.98 ALDH1A1 (0.83) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL63373 0.98 ALDH1A1 (0.83) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL8836596 0.96 ALDH1A1 (0.87) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
Benzene SCHEMBL9434273 0.96 MAOB (0.83) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL29558001 0.96 ALDH1A1 (0.87) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL707839 0.96 ALDH1A1 (0.87) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL8645103 0.96 ALDH1A1 (0.79) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1400552-B1 Polyimide compositions useful as dielectric substrates for electronic applications, and methods relating thereto DU PONT (US) 2008-12-03 EP claimed
EP-1182222-B1 Polyimide film, method of manufacture, and metal interconnect board with polyimide film substrate DUPONT TORAY CO LTD (JP) 2003-06-04 EP claimed
EP-1184407-B1 Polyimide film, method of manufacture, and metal interconnect board with polyimide film substrate DUPONT TORAY CO LTD (JP) 2006-06-07 EP disclosed