SCHEMBL465790

SCHEMBL465790

C=Cc1ccccc1N=C=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
ALDH1A1 P00352 3/20 0.40
TRPA1 O75762 1/20 0.33
TSHR P16473 2/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762531 0.92 CYP3A4 (0.47) CYP3A4ALDH1A1TRPA1TSHRALOX15
SCHEMBL15528637 0.83 CYP3A4 (0.47) CYP3A4ALDH1A1TRPA1TDP1MEN1
SCHEMBL31168163 0.83 CYP3A4 (0.50) CYP3A4ALDH1A1TRPA1TSHRTDP1
SCHEMBL10890112 0.83 CYP3A4 (0.50) CYP3A4ALDH1A1TRPA1TSHRTDP1
SCHEMBL3099538 0.83 CYP3A4 (0.50) CYP3A4ALDH1A1TRPA1TSHRTDP1
SCHEMBL5551100 0.83 CYP3A4 (0.50) CYP3A4ALDH1A1TRPA1TSHRTDP1
SCHEMBL19891826 0.82 CYP3A4 (0.47) CYP3A4ALDH1A1TRPA1GABRA1GABRB2
SCHEMBL9585196 0.82 CYP3A4 (0.47) CYP3A4ALDH1A1TRPA1GABRA1GABRB2
SCHEMBL9918938 0.81 CYP3A4 (0.66) CYP3A4ALDH1A1TRPA1TDP1HPGD
SCHEMBL7190691 0.81 TDP1 (0.50) CYP3A4ALDH1A1TRPA1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330640-A Preparation method for high chemical purity lactide CHANGCHUN APPLIED CHEMISTRY 2016-02-17 CN claimed
CN-104640900-A Preparation method of thiourethane optical material KOC SOLUTION CO LTD 2015-05-20 CN claimed
CN-102464626-B Method for preparing 5-(4-(N,N-diphenyl-amino) phenmethylene)-3-(2-phenethyl)-2,4-oxazolidinedione SHENYANG PHOTOSENSITIVE CHEMICAL RES INST 2014-03-12 CN claimed
CN-102464626-A Preparation method of 5- (4- (N, N-diphenylamino) benzylidene) -3- (2-phenylethyl) -2, 4-oxazolidinedione SHENYANG PHOTOSENSITIVE CHEMICAL RES INST 2012-05-23 CN claimed
EP-1498404-B1 SEPARATING AGENT FOR OPTICAL ISOMER AND METHOD FOR PREPARATION THEREOF DAICEL CHEM (JP) 2007-08-08 EP claimed
EP-0361229-B1 Polymer-bonded dyes, process for their preparation and their use BAYER AG (DE) 1994-04-27 EP claimed
EP-0455585-B1 Unsaturated urea polysiloxanes CIBA GEIGY AG (CH) 1994-03-23 EP claimed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
EP-0455585-A1 Unsaturated urea polysiloxanes CIBA-GEIGY AG (CH) 1991-11-06 EP claimed
US-12403447-B2 Separating agent for optical isomers DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-20240382933-A1 METHOD FOR PRODUCING STATIONARY PHASE FOR COLUMN CHROMATOGRAPHY DAICEL CORPORATION (JP) 2024-11-21 US disclosed
EP-4410420-A1 METHOD FOR PRODUCING STATIONARY PHASE FOR COLUMN CHROMATOGRAPHY Daicel Corporation (JP) 2024-08-07 EP disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
EP-0082355-B1 SEMIPERMEABLE MEMBRANES OF MODIFIED POLYSTYRENE, PROCESS FOR THEIR MANUFACTURE AND THEIR USE ALIGENA AG (CH) 1986-06-11 EP disclosed
US-4397993-A Curable oxirane polymers THE DOW CHEMICAL COMPANY (US) 1983-08-09 US disclosed
EP-0082355-A2 Semipermeable membranes of modified polystyrene, process for their manufacture and their use ALIGENA AG (CH) 1983-06-29 EP disclosed
US-4264483-A AN ACRYLIC MONOMER OR OLIGOMER, PHOTOREACTIVE RESIN, PHOTOINITIATOR, FREE RADICAL INHIBITOR, PIGMENT WHITTAKER CORPORATION (US) 1981-04-28 US disclosed
US-4031066-A Flexible polybutadiene resin composition having excellent electrical properties NIPPON SODA COMPANY LIMITED (JA) 1977-06-21 US disclosed
US-3728369-A STABILIZATION OF VINYL ISOCYANATES DOW CHEMICAL CO 1973-04-17 US disclosed