SCHEMBL9585196

SCHEMBL9585196

C=Cc1cccc(N=C=O)c1N=C=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.47
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
ALDH1A1 P00352 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465790 0.82 CYP3A4 (0.47) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL7762531 0.82 CYP3A4 (0.47) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL19891826 0.81 CYP3A4 (0.47) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL9918938 0.80 CYP3A4 (0.66) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL109280 0.80 CYP3A4 (0.62) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL18422183 0.78 ALDH1A1 (0.43) CYP3A4GABRA1GABRB2ALDH1A1
SCHEMBL28307637 0.76 GABRA1 (0.35) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL8964677 0.76 CYP3A4 (0.54) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL7209613 0.76 CYP3A4 (0.42) CYP3A4GABRA1GABRB2TRPA1
SCHEMBL10435654 0.75 CYP3A4 (0.52) CYP3A4GABRA1GABRB2ALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
EP-3135703-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2019-10-16 EP disclosed
EP-3135703-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2017-03-01 EP disclosed
US-20170029553-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL, AND METHOD OF MANUFACTURING OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2017-02-02 US disclosed
CN-106164124-A The manufacture method of polymerizable composition for optical material, optical material and optical material 三井化学株式会社 2016-11-23 CN disclosed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US disclosed
US-4552917-A Modified polyurethane liquid polymer compositions OLIN CORPORATION (US) 1985-11-12 US disclosed