25-Hydroxyergocalciferol-

25-Hydroxyergocalciferol-

SCHEMBL465799

C=C1CC[C@H](O)CC1=CC=C1CCC[C@@]2(C)C1CC[C@@H]2[C@H](C)C=C[C@H](C)C(C)(C)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.78
ALOX15 P16050 3/20 0.78
CYP3A4 P08684 3/20 0.78
LMNA P02545 2/20 0.78
HSPD1 P10809 2/20 0.78
PTGS1 P23219 2/20 0.78
HSPE1 P61604 2/20 0.78
ADRA1A P35348 2/20 0.78
AR P10275 1/20 0.78
TSHR P16473 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
USP2 O75604 1/20 0.78
ABCB11 O95342 1/20 0.78
ESR1 P03372 1/20 0.78
TST Q16762 1/20 0.78
MAPT P10636 3/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
SREBF1 P36956 1/20 0.68
VDR P11473 4/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
25-Hydroxyergocalciferol- SCHEMBL15981129 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL19469428 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL15981131 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL10034123 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL285346 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL9933379 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL12464610 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL17274134 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL1879846 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1
25-Hydroxyergocalciferol- SCHEMBL9933381 1.00 ALDH1A1 (0.78) ALDH1A1ALOX15CYP3A4LMNAHSPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150272967-A1 EXTREMELY HIGH LOADING DOSE GRASSO FRANK J (US) 2015-10-01 US claimed
WO-2015102996-A1 EXTREMELY HIGH LOADING DOSE GRASSO FRANK J (US) 2015-07-09 WO claimed
EP-1695095-B1 METHOD FOR THE DETERMINATION OF 25-HYDROXYCHOLECALCIFEROL IN FEED DSM IP ASSETS BV (NL) 2010-10-20 EP claimed
US-20090088373-A1 USE OF COMPOSITIONS TO ENHANCE INNATE IMMUNE RESPONSE BVR TECHNOLOGIES CO. 2009-04-02 US claimed
US-7358092-B2 Method for the determination of 25-hydroxycholecalciferol in feed DSM IP ASSETS B.V. (NL) 2008-04-15 US claimed
US-20080038374-A1 New Use LIPOPEPTIDE AB (SE) 2008-02-14 US claimed
US-20070117209-A1 Radio-labeled analyte; aqueous dispersion; liquid chromatography, mass spectrometry DSM IP ASSETS B.V. (NL) 2007-05-24 US claimed
EP-1695095-A2 METHOD FOR THE DETERMINATION OF 25-HYDROXYCHOLECALCIFEROL IN FEED DSMIP Assets B.V. (NL) 2006-08-30 EP claimed
WO-2005059565-A2 METHOD FOR THE DETERMINATION OF 25-HYDROXYCHOLECALCIFEROL IN FEED DSM IP ASSETS B.V. (NL) 2005-06-30 WO claimed
EP-0710112-B1 Use of vitamin D and derivatives thereof for the manufacture of a medicament for protection against neuron loss UNIV KENTUCKY (US) 2001-12-05 EP claimed
US-5939407-A VITAMIN D RECEPTORS FOR NERVOUS SYSTEM DISORDERS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1999-08-17 US claimed
EP-0710112-A1 Use of vitamin D and derivatives thereof for the manufacture of a medicament for protection against neuron loss BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) 1996-05-08 EP claimed
WO-1995002409-A2 USE OF VITAMIN D AND DERIVATIVES THEREOF FOR THE MANUFACTURE OF A MEDICAMENT FOR PROTECTION AGAINST NEURON LOSS BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) 1995-01-26 WO claimed
US-4330537-A PHOSPHONATE COMPOUNDS AND VITAMIN D DERIVATIVES USEFUL AGAINST OSTEOPORSIS THE PROCTER & GAMBLE COMPANY (US) 1982-05-18 US claimed
US-4310522-A THICKENED EGG SHELLS COMPRISING CALCIUM SOURCE AND A HYDROXY CHOLECALCIFEROL THE UPJOHN COMPANY (US) 1982-01-12 US claimed
US-4230700-A ADMINISTERING AN ORGANIC MONO- OR DIPHOSPHONATE AND A VITAMIN-D-LIKE ANTIRACHITIC COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1980-10-28 US claimed
US-4012509-A HYDROXY-CHOLECALCIFEROLS, -TACHYSTEROLS, -ERGOCALCIFEROLS AND THEIR ACYLATES; EGG SHELL THICKNESS THE UPJOHN COMPANY (US) 1977-03-15 US claimed
US-20250235528-A1 VACCINE COMPOSITION COMPRISING AN ANTIGEN AND A TLR3 AGONIST ISR IMMUNE SYSTEM REGULATION HOLDING AB PUBL (SE) 2025-07-24 US disclosed
US-4310522-A THICKENED EGG SHELLS COMPRISING CALCIUM SOURCE AND A HYDROXY CHOLECALCIFEROL THE UPJOHN COMPANY (US) 1982-01-12 US disclosed
US-4012509-A HYDROXY-CHOLECALCIFEROLS, -TACHYSTEROLS, -ERGOCALCIFEROLS AND THEIR ACYLATES; EGG SHELL THICKNESS THE UPJOHN COMPANY (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088373-A1 USE OF COMPOSITIONS TO ENHANCE INNATE IMMUNE RESPONSE MYD88, MTOR, TLR3 ALDH1A1 4871/4885ALOX15 1052/4885CYP3A4 3157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.