Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660330 | 1.00 | NSD2 (0.52) | NSD2SLC6A2SLC6A4SNCAMEN1 | |
| SCHEMBL1035347 | 0.74 | NSD2 (0.69) | NSD2SLC6A2SLC6A4MEN1NPC1 | |
| SCHEMBL7401773 | 0.72 | HTT (0.51) | NSD2SNCAMEN1NPC1KMT2A | |
| SCHEMBL7464731 | 0.72 | SNCA (0.58) | NSD2SNCAMEN1NPC1KMT2A | |
| SCHEMBL27491746 | 0.71 | MEN1 (0.50) | NSD2SNCAMEN1NPC1KMT2A | |
| SCHEMBL1816851 | 0.71 | HTT (0.41) | SLC6A2SLC6A4KMT2AHTTGAA | |
| Hydrochloric Acid SCHEMBL14052852 | 0.70 | HTT (0.40) | NSD2SLC6A2SLC6A4KMT2AHTT | |
| SCHEMBL5118098 | 0.69 | NSD2 (0.63) | NSD2SLC6A2SLC6A4SNCAMEN1 | |
| SCHEMBL11120129 | 0.68 | SNCA (0.47) | NSD2SLC6A2SLC6A4SNCAMEN1 | |
| SCHEMBL16235374 | 0.68 | NSD2 (0.55) | NSD2SLC6A2SLC6A4MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319206-A1 | Process for Preparing Protected Amidines | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | claimed |
| EP-1856035-B1 | PROCESS FOR PREPARAING PROTECTED AMIIDINES | ASTRAZENECA AB (SE) | 2008-12-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319206-A1 | Process for Preparing Protected Amidines | HK1, HRH4, PYM1 | NSD2 483/4885SLC6A2 1887/4885SLC6A4 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.