Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658246 | 1.00 | CTSS (0.39) | CTSSCTSKANO1ALDH1A1LMNA | |
| SCHEMBL4598490 | 0.90 | CTSS (0.50) | CTSSCTSKALDH1A1PTPN1 | |
| SCHEMBL4598875 | 0.80 | CTSS (0.52) | CTSSCTSKPTPN1 | |
| SCHEMBL4656188 | 0.78 | CTSS (0.51) | CTSSCTSKANO1ALDH1A1PTPN1 | |
| SCHEMBL4656187 | 0.78 | CTSS (0.51) | CTSSCTSKANO1ALDH1A1PTPN1 | |
| SCHEMBL4598288 | 0.78 | PARP15 (0.40) | ANO1ALDH1A1LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4610508 | 0.77 | PARP15 (0.39) | ANO1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4930753 | 0.76 | CTSS (0.44) | CTSSCTSKANO1ALDH1A1LMNA | |
| SCHEMBL4930745 | 0.76 | CTSS (0.44) | CTSSCTSKANO1ALDH1A1LMNA | |
| SCHEMBL4598159 | 0.75 | CTSS (0.52) | CTSSCTSKPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910274-A1 | PHENYL COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015807-A1 | PHENYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |