Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 18/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613550 | 0.89 | RBP4 (0.54) | RBP4 | |
| Hydrochloric Acid SCHEMBL614973 | 0.88 | RBP4 (0.53) | RBP4CNR1 | |
| SCHEMBL613346 | 0.85 | RBP4 (0.56) | RBP4 | |
| SCHEMBL612849 | 0.84 | RBP4 (0.56) | RBP4 | |
| SCHEMBL614158 | 0.82 | AVPR1A (0.58) | RBP4CNR1 | |
| SCHEMBL614129 | 0.82 | AVPR1A (0.57) | RBP4CNR1 | |
| SCHEMBL614775 | 0.82 | RBP4 (0.53) | RBP4CNR1 | |
| SCHEMBL28771346 | 0.80 | RBP4 (0.49) | RBP4CNR1 | |
| SCHEMBL10209490 | 0.79 | RBP4 (0.51) | RBP4CNR1 | |
| SCHEMBL615322 | 0.79 | RBP4 (0.51) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917255-A2 | INDOL-3-YL-CARBONYL-PIPERIDIN AND PIPERAZIN DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007014851-A2 | INDOL-3-YL-CARBONYL-PIPERIDIN AND PIPERAZIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-08 | — | — | WO | disclosed |