Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658447 | 1.00 | ANO1 (0.42) | ANO1MEN1PKMKMT2APOLB | |
| Hydrochloric Acid SCHEMBL4929069 | 0.99 | ANO1 (0.41) | ANO1MEN1PKMKMT2APOLB | |
| SCHEMBL4928293 | 0.84 | CTSS (0.43) | ANO1MEN1PKMKMT2AF11 | |
| SCHEMBL4928298 | 0.84 | CTSS (0.43) | ANO1MEN1PKMKMT2AF11 | |
| SCHEMBL4611104 | 0.79 | ANO1 (0.42) | ANO1MEN1PKMKMT2APOLB | |
| SCHEMBL4611099 | 0.79 | ANO1 (0.42) | ANO1MEN1PKMKMT2APOLB | |
| SCHEMBL268086 | 0.79 | LMNA (0.43) | ANO1MEN1KMT2ADPP4 | |
| Hydrochloric Acid SCHEMBL4919638 | 0.78 | ANO1 (0.41) | ANO1MEN1PKMKMT2APOLB | |
| SCHEMBL4598288 | 0.78 | PARP15 (0.40) | ANO1MEN1PKMKMT2ADPP4 | |
| SCHEMBL4598495 | 0.77 | ANO1 (0.44) | ANO1POLBAPEX1DPP4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910274-A1 | PHENYL COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015807-A1 | PHENYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |