Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657428 | 0.86 | ALDH1A1 (0.39) | TAAR1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL4657442 | 0.80 | LOXL2 (0.39) | TAAR1IDO1MAOBMAOAAGXT | |
| SCHEMBL4656221 | 0.78 | LOXL2 (0.47) | ALDH1A1TSHRSMN1; SMN2IDO1GAA | |
| SCHEMBL4657528 | 0.78 | HTR2A (0.35) | TAAR1IDO1MAOBMAOA | |
| SCHEMBL4656045 | 0.78 | SLC6A4 (0.40) | TAAR1ALDH1A1IDO1MAOBMAOA | |
| SCHEMBL6825243 | 0.77 | ALDH1A1 (0.51) | TAAR1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL4657483 | 0.77 | TAAR1 (0.43) | TAAR1ALDH1A1IDO1MAOBMIF | |
| SCHEMBL27597564 | 0.76 | APP (0.46) | APPTAAR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL11092821 | 0.74 | IDO1 (0.41) | APPTAAR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL4655991 | 0.72 | LOXL2 (0.46) | ALDH1A1TSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385817-B1 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-7402691-B2 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-22 | — | — | US | disclosed |
| US-7011838-B2 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-14 | — | — | US | disclosed |
| US-20050209323-A1 | Malononitrile compounds and their use as pesticides | OTAKA KEN | 2005-09-22 | — | — | US | disclosed |
| US-20040138065-A1 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1385817-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090320-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209323-A1 | Malononitrile compounds and their use as pesticides | C1S, C1R, C5 | APP 1201/4885TAAR1 644/4885ALDH1A1 1502/4885 |
| US-20040138065-A1 | Malononitrile compounds and their use as pesticides | CBR1, MAL2, CBR3 | APP 2812/4885TAAR1 632/4885ALDH1A1 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.