Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20496732 | 0.92 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL30694100 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL5172812 | 0.85 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL29736247 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL4061067 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL2477531 | 0.83 | GAA (0.68) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL10187274 | 0.83 | MAPT (0.68) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL10188110 | 0.81 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTGAAHTT | |
| Hydrochloric Acid SCHEMBL6258876 | 0.81 | GAA (0.71) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL5649965 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |
| EP-2001557-A2 | REDUCTIVE COLOUR REMOVAL | Henkel AG & Co. KGaA (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107309-A2 | REDUCTIVE COLOUR REMOVAL | HENKEL AG & CO. KGAA (DE) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007019930-A1 | AGENT FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-02-22 | — | — | WO | disclosed |