Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6258876 | 0.98 | GAA (0.71) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL4729328 | 0.91 | GAA (0.66) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL8099817 | 0.90 | GAA (0.74) | GAAMAPTKDM4EALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL11224670 | 0.88 | ALDH1A1 (0.78) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL4061067 | 0.86 | ALDH1A1 (0.55) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL29736247 | 0.86 | ALDH1A1 (0.55) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL11228216 | 0.85 | ALDH1A1 (0.49) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL29835019 | 0.85 | ALDH1A1 (0.49) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL6843117 | 0.84 | GAA (0.67) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL11218926 | 0.84 | GAA (0.71) | GAAMAPTKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| CN-100549003-C | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2009-10-14 | — | — | CN | claimed |
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | claimed |
| CN-100358887-C | m-aminophenol derivatives and dyes containing these compounds | P & G CLAIROL INC (US) | 2008-01-02 | — | — | CN | claimed |
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | claimed |
| CN-100349886-C | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2007-11-21 | — | — | CN | claimed |
| US-7294151-B2 | Means and method for dyeing keratin fibres | WELLA AG (DE) | 2007-11-13 | — | — | US | claimed |
| US-7291183-B2 | Agent and method for dyeing keratin fibers | WELLA AG (DE) | 2007-11-06 | — | — | US | claimed |
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | claimed |
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-02 | — | — | US | claimed |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-09-18 | — | — | US | claimed |
| CN-1443154-A | 3- (2, 5-diaminophenyl) -acrylamide derivatives and coloring agents containing said compounds | WELLA AG (DE) | 2003-09-17 | — | — | CN | claimed |
| CN-1437578-A | (P-amino-hyaroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2003-08-20 | — | — | CN | claimed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | claimed |
| EP-1166749-A2 | Composition and process for dyeing keratinic fibres | Wella Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | claimed |
| US-4330292-A | CONTAINING AN OXIDATION BASE | L'OREAL (FR) | 1982-05-18 | — | — | US | claimed |
| US-4305717-A | P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES | L'OREAL (FR) | 1981-12-15 | — | — | US | claimed |
| US-4094635-A | Meta-aminophenol sulfonamides as couplers in hair dye compositions | L'OREAL (FR) | 1978-06-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | KRT18, MKI67, F12 | GAA 1709/4885MAPT 661/4885KDM4E 1060/4885 |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | GAA 1281/4885MAPT 755/4885KDM4E 4413/4885 |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | AOC1, DPYD, NDUFB4 | GAA 2196/4885MAPT 898/4885KDM4E 2236/4885 |
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | KRT18, S100A4, CKAP4 | GAA 3403/4885MAPT 460/4885KDM4E 251/4885 |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | GAA 3318/4885MAPT 666/4885KDM4E 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.