Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 10/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22583430 | 0.81 | RAB9A (0.62) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL2779146 | 0.81 | MAPT (1.00) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL7368441 | 0.81 | L3MBTL1 (0.69) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL2782667 | 0.79 | RAB9A (0.59) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL31680416 | 0.79 | RAB9A (0.59) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| Iodide SCHEMBL2782687 | 0.77 | RAB9A (0.57) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL16571322 | 0.77 | PLAU (0.49) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL28703760 | 0.77 | RAB9A (0.81) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL29376441 | 0.77 | RAB9A (0.81) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL1558713 | 0.77 | RAB9A (0.70) | L3MBTL1MAPTRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917244-A2 | HETARYL-SUBSTITUTED GUANIDINE COMPOUNDS AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5-RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022964-A2 | HETARYL-SUBSTITUTED GUANIDINE COMPOUNDS AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5-RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |