Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624592 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL28743518 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL28743513 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL874054 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL2483134 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL855493 | 0.79 | KDM4E (0.53) | KDM4EATMALDH1A1HTTLMNA | |
| SCHEMBL29729049 | 0.79 | KDM4E (0.53) | KDM4EATMALDH1A1HTTLMNA | |
| SCHEMBL8481621 | 0.78 | ALDH1A1 (0.71) | KDM4EALDH1A1PPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL3562522 | 0.78 | KDM4E (0.52) | KDM4EATMALDH1A1HTTLMNA | |
| SCHEMBL988997 | 0.78 | KDM4E (0.72) | KDM4EATMLMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | claimed |