Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | P4HB | P07237 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659805 | 0.90 | BCHE (0.50) | BCHETYRACHEP4HBADRA2A | |
| SCHEMBL4659820 | 0.83 | BCHE (0.60) | BCHETYRACHEKDM4EMAPT | |
| SCHEMBL4659816 | 0.81 | TYR (0.45) | BCHETYRACHECA1CA2 | |
| SCHEMBL4596682 | 0.80 | TYR (0.61) | BCHETYRACHEKDM4EMAPT | |
| SCHEMBL13493018 | 0.78 | ADRA2A (0.53) | BCHETYRACHEADRA2AADRA1A | |
| SCHEMBL4660955 | 0.78 | TYR (0.53) | BCHETYRACHEKDM4EMAPT | |
| SCHEMBL8034147 | 0.77 | SMN1; SMN2 (0.47) | KDM4EMAPT | |
| SCHEMBL9082001 | 0.74 | ADRA2A (0.51) | BCHETYRACHEADRA2AADRA1A | |
| SCHEMBL4660873 | 0.73 | TYR (0.54) | BCHETYRACHEKDM4E | |
| SCHEMBL4661020 | 0.73 | BCHE (0.65) | BCHETYRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748767-A4 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS INC (US) | 2008-12-24 | — | — | EP | disclosed |
| EP-1748767-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | Unigen Pharmaceuticals, Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005117849-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |