Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031378 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTTSHRRAB9A | |
| SCHEMBL4659696 | 0.77 | BCHE (0.58) | MAPTKDM4E | |
| SCHEMBL8018549 | 0.77 | CHRM2 (0.42) | ALDH1A1MAPTTSHRSYKRAB9A | |
| SCHEMBL4659805 | 0.76 | BCHE (0.50) | SMN1; SMN2ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL20681679 | 0.75 | RAB9A (0.45) | SMN1; SMN2ALDH1A1MAPTTSHRSYK | |
| SCHEMBL6291795 | 0.73 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTTSHRSYK | |
| SCHEMBL13493018 | 0.73 | ADRA2A (0.53) | KMT2AMEN1 | |
| SCHEMBL23610044 | 0.73 | ADRA2A (0.50) | SMN1; SMN2ALDH1A1MAPTTSHRSYK | |
| SCHEMBL31143602 | 0.73 | ADRA2A (0.50) | SMN1; SMN2ALDH1A1MAPTTSHRSYK | |
| SCHEMBL23610042 | 0.73 | ADRA2A (0.50) | SMN1; SMN2ALDH1A1MAPTTSHRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073269-A2 | NICOTINE RECEPTOR LIGANDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2000-12-07 | — | — | WO | disclosed |