Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 5/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762894 | 0.89 | TP53 (0.36) | HTT | |
| SCHEMBL5151373 | 0.88 | CA1 (0.41) | MCL1PTGESALOX5RORCPTPN22 | |
| SCHEMBL4762138 | 0.85 | MCL1 (0.45) | MCL1PTGESALOX5RORCPTPN22 | |
| SCHEMBL4792514 | 0.83 | MCL1 (0.41) | MCL1PTGESALOX5RORCPTPN22 | |
| SCHEMBL4762404 | 0.82 | BRD4 (0.42) | — | |
| SCHEMBL3947584 | 0.82 | BRD4 (0.48) | — | |
| SCHEMBL5151586 | 0.80 | CA1 (0.40) | MCL1RORCOXTRAVPR1AGAA | |
| SCHEMBL4762136 | 0.78 | MCL1 (0.49) | MCL1PTGESALOX5RORCPTPN22 | |
| SCHEMBL5149450 | 0.77 | CA1 (0.42) | GAAHTT | |
| SCHEMBL3941796 | 0.76 | BRD4 (0.43) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |