Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 5/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.44 |
| ▸ | MAP2 | P11137 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152108 | 0.87 | CA1 (0.43) | MCL1PTGESALOX5KDM4EALDH1A1 | |
| SCHEMBL5156271 | 0.87 | CA1 (0.43) | MCL1PTGESALOX5KDM4EMEN1 | |
| SCHEMBL5149891 | 0.87 | RORC (0.47) | ALOX5KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL4762138 | 0.87 | MCL1 (0.45) | MCL1PTGESALOX5ALDH1A1HTT | |
| SCHEMBL5151357 | 0.86 | KDM4E (0.51) | KDM4EMEN1ALDH1A1HPGDHTT | |
| SCHEMBL5151373 | 0.84 | CA1 (0.41) | MCL1PTGESALOX5MEN1KMT2A | |
| SCHEMBL4792514 | 0.80 | MCL1 (0.41) | MCL1PTGESALOX5HTTPTPN22 | |
| SCHEMBL4659730 | 0.78 | MCL1 (0.37) | MCL1PTGESALOX5HTTPTPN22 | |
| SCHEMBL5152512 | 0.78 | PTGDR2 (0.43) | KDM4EMEN1ALDH1A1HPGDHTT | |
| SCHEMBL5151594 | 0.77 | ALDH1A1 (0.56) | KDM4EMEN1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| US-20070225284-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |
| US-20070225284-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225284-A1 | Inhibitors of soluble adenylate cyclase | ADCY1, ADCY2, ADCYAP1R1 | MCL1 4033/4885PTGES 105/4885ALOX5 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.