SCHEMBL4660305

SCHEMBL4660305

Cc1ccc(CC(=O)N2CCC(CCC(C(=O)c3ncco3)C(CCC(=O)c3ncco3)C3CCN(C(=O)Cc4cccc(C)c4)CC3)CC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.56
GRIN2B Q13224 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4659214 0.84 FAAH (0.55) FAAH
SCHEMBL4187188 0.82 FAAH (0.79) FAAH
SCHEMBL4660422 0.80 FAAH (0.62) FAAH
SCHEMBL4190716 0.78 FAAH (0.81) FAAH
SCHEMBL4189658 0.73 FAAH (1.00) FAAH
SCHEMBL4189644 0.72 FAAH (0.79) FAAH
SCHEMBL4193935 0.71 FAAH (0.82) FAAH
SCHEMBL4659049 0.71 FAAH (0.62) FAAH
SCHEMBL4189376 0.70 FAAH (1.00) FAAH
SCHEMBL4182538 0.70 FAAH (0.81) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954137-A4 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA NV (BE) 2008-12-17 EP claimed
EP-1954137-A2 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2008-08-13 EP claimed
WO-2007061862-A2 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-31 WO claimed