Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | C5 | P01031 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660367 | 0.88 | LMNA (0.67) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL4660216 | 0.84 | LMNA (0.65) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL4660277 | 0.79 | LMNA (0.64) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL10970830 | 0.78 | LMNA (0.59) | LMNAMAPTALDH1A1KMT2AC5 | |
| SCHEMBL4661694 | 0.77 | LMNA (0.64) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL4660272 | 0.76 | LMNA (0.70) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL4660398 | 0.75 | LMNA (0.68) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL4662710 | 0.74 | LMNA (0.60) | LMNAMAPTALDH1A1KMT2APPARG | |
| SCHEMBL4662887 | 0.74 | LMNA (0.71) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL4661580 | 0.74 | LMNA (0.71) | LMNAMAPTALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427697-B1 | SULPHONATION OF PHENOLS | GREAT LAKES CHEMICAL EUROP (CH) | 2008-12-24 | — | — | EP | disclosed |