SCHEMBL4660385

SCHEMBL4660385

CC1CC(CO)CC(C)(C)C1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.43
APLNR P35414 2/20 0.36
ALDH1A1 P00352 3/20 0.35
HTT P42858 1/20 0.33
LMNA P02545 3/20 0.32
CYP3A4 P08684 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NR1I2 O75469 1/20 0.30
ABCB11 O95342 1/20 0.30
PPP1CA P62136 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2345297 0.83 ALDH1A1 (0.33) EPHX2ALDH1A1HTTLMNACYP3A4
SCHEMBL17049037 0.80
SCHEMBL4776432 0.79 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL4771606 0.79 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL20312878 0.79 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL4771599 0.79 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL4771611 0.79 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL4776437 0.79 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL10405926 0.78 ALDH1A1 (0.33) ALDH1A1HTTLMNACYP3A4CYP1A2
SCHEMBL6446886 0.77 EPHX2 (0.43) EPHX2ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341512-B1 RHINOLOGICAL AGENTS SYMRISE GMBH & CO KG (DE) 2008-12-31 EP claimed
EP-1341512-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2003-09-10 EP claimed
WO-2002041861-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2002-05-30 WO claimed
CN-115286497-A Preparation method of 3,3,5-trimethylcyclohexanone 中国天辰工程有限公司 2022-11-04 CN disclosed
EP-1341512-B1 RHINOLOGICAL AGENTS SYMRISE GMBH & CO KG (DE) 2008-12-31 EP disclosed
EP-1341512-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2003-09-10 EP disclosed
WO-2002041861-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2002-05-30 WO disclosed