Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771599 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTTCTDSP1 | |
| SCHEMBL4776437 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTTCTDSP1 | |
| SCHEMBL4771606 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTTCTDSP1 | |
| SCHEMBL4771611 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTTCTDSP1 | |
| SCHEMBL28189300 | 0.82 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL20312878 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL6446886 | 0.79 | EPHX2 (0.43) | ALDH1A1HTT | |
| SCHEMBL4660385 | 0.79 | EPHX2 (0.43) | ALDH1A1HTT | |
| SCHEMBL19021206 | 0.79 | — | — | |
| SCHEMBL11374368 | 0.79 | CYP1A2 (0.39) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682109-B1 | THE USE OF 1-AMINOCYCLOHEXANE DERIVATIVES TO MODIFY DEPOSITION OF FIBRILLOGENIC AS PEPTIDES IN AMYLOIDOPATHIES | MERZ PHARMA GMBH & CO KGAA (DE) | 2008-10-15 | — | — | EP | claimed |
| CN-1264827-C | 1-cyclic amino-alkylcyclohexane compounds, pharmaceutical compositions thereof and their use as anticonvulsants | MERZ & CO GMBH & CO (DE) | 2006-07-19 | — | — | CN | disclosed |
| CN-1374956-A | 1-cyclic amino-alkylcyclohexane compounds, pharmaceutical compositions thereof and their use as anticonvulsants | MERZ & CO GMBH & CO (DE) | 2002-10-16 | — | — | CN | disclosed |