Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427139 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL8165019 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL3611978 | 0.81 | TSHR (0.48) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL2724197 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| Itaconate SCHEMBL7044038 | 0.81 | ALOX15 (0.46) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL8404863 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| Oxalic Acid SCHEMBL28735102 | 0.79 | TSHR (0.52) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL985178 | 0.79 | TSHR (0.55) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| Methacrylic Acid SCHEMBL21811308 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| Methacrylic Acid SCHEMBL2937502 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPK1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758542-B2 | Protein chromatography matrices with hydrophilic copolymer coatings | PURDUE RESEARCH FOUNDATION (US) | 2017-09-12 | — | — | US | claimed |
| WO-2015128475-A1 | NOVEL COATED CARRIERS FOR THE SPECIFIC BINDING OF TARGET MOLECULES | LEUKOCARE AG (DE) | 2015-09-03 | — | — | WO | claimed |
| EP-2913671-A1 | Novel coated carriers for the specific binding of target molecules | LEUKOCARE AG (DE) | 2015-09-02 | — | — | EP | claimed |
| US-20140316108-A1 | Protein Chromatography Matrices with Hydrophilic Copolymer Coatings | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-10-23 | — | — | US | claimed |
| EP-2773455-A1 | PROTEIN CHROMATOGRAPHY MATRICES WITH HYDROPHILIC COPOLYMER COATINGS | Purdue Research Foundation (US) | 2014-09-10 | — | — | EP | claimed |
| WO-2013067171-A1 | PROTEIN CHROMATOGRAPHY MATRICES WITH HYDROPHILIC COPOLYMER COATINGS | PURDUE RESEARCH FOUNDATION (US) | 2013-05-10 | — | — | WO | claimed |
| US-20030152786-A1 | Silicon containing compounds from michael-type addition reactions useful as monomers and macromers | BIOCOMPATIBLES UK LIMITED (GB) | 2003-08-14 | — | — | US | claimed |
| JP-2003522227-A | — | — | 2003-07-22 | — | — | JP | claimed |
| EP-1255761-A1 | SILICON CONTAINING COMPOUNDS FROM MICHAEL - TYPE ADDITION REACTIONS USEFUL AS MONOMERS AND MACROMERS | BIOCOMPATIBLES LTD. (GB) | 2002-11-13 | — | — | EP | claimed |
| WO-2001057048-A1 | SILICON CONTAINING COMPOUNDS FROM MICHAEL - TYPE ADDITION REACTIONS USEFUL AS MONOMERS AND MACROMERS | BIOCOMPATIBLES LIMITED (GB) | 2001-08-09 | — | — | WO | claimed |
| US-11879097-B2 | Photochromic compound, curable composition containing said photochromic compound, and optical article | TOKUYAMA CORPORATION (JP) | 2024-01-23 | — | — | US | disclosed |
| US-20230280500-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC CURABLE COMPOSITION, CURED BODY, LENS AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2023-09-07 | — | — | US | disclosed |
| US-20230260669-A1 | CURABLE COMPOSITION AND CURED BODY OF SAME | TOKUYAMA CORPORATION (JP) | 2023-08-17 | — | — | US | disclosed |
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |
| EP-0965628-A1 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5808100-A | DURABILITY | TOKUYAMA CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0778276-A1 | Photochromic chromene derivatives | TOKUYAMA CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |