SCHEMBL4660966

SCHEMBL4660966

COc1c(F)c(F)c(-c2[c]c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970170 0.82
SCHEMBL15757740 0.79 HSD17B10 (0.39) HSD17B10
SCHEMBL3952376 0.75
SCHEMBL12965347 0.75 HSD17B10 (0.45) HSD17B10
SCHEMBL3957062 0.74
SCHEMBL5364219 0.73
SCHEMBL716940 0.73 HSD17B10 (0.31) HSD17B10
SCHEMBL1711725 0.72 HSD17B10 (0.47) HSD17B10
SCHEMBL182607 0.72 HSD17B10 (0.40) HSD17B10
SCHEMBL3957066 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730156-B1 PROCESS FOR PRODUCING TETRAKIS(FLUOROARYL)BORATE SALTS ALBEMARLE CORP (US) 2008-12-17 EP disclosed
US-20070197831-A1 Process for producing tetrakis(faryl)borate-salts LEE JOHN Y 2007-08-23 US disclosed
EP-1730156-A1 PROCESS FOR PRODUCING TETRAKIS(FLUOROARYL)BORATE SALTS ALBEMARLE CORPORATION (US) 2006-12-13 EP disclosed
US-7087780-B2 Process for producing tetrakis(Faryl)borate salts ALBEMARLE CORPORATION (US) 2006-08-08 US disclosed
EP-1549656-B1 PROCESS FOR PRODUCING TETRAKIS(\"F\"-ARYL)BORATE SALTS ALBEMARLE CORP (US) 2006-07-12 EP disclosed
WO-2005105816-A1 PROCESS FOR PRODUCING TETRAKIS (FLUOROARYL) BORATE-SALTS ALBEMARLE CORPORATION (US) 2005-11-10 WO disclosed
US-6831200-B2 A liquid ethereal or hydrocarbyl medium of a solution of an alkali metal tetrakis(Faryl)borate is substituted with a halogenated hydrocarbon, without isolating alkali metal tetrakis/Faryl/borate, mixing an onium salt; mitigates both the thermal and shock sensitivity of alkali borate ALBEMARLE CORPORATION 2004-12-14 US disclosed
US-20040230075-A1 Process for producing tetrakis(Faryl)borate salts W. R. GRACE & CO-CONN. 2004-11-18 US disclosed
US-20040068134-A1 Process for producing tetrakis(Faryl)borate salts ALBEMARLE CORPORATION 2004-04-08 US disclosed
US-6388138-B1 Process for producing a magnesium di[tetrakis(Faryl)borate] and products therefrom ALBEMARLE CORPORATION 2002-05-14 US disclosed
US-6365773-B1 Process for producing fluoroaromatic carboxylates ALBEMARLE CORPORATION 2002-04-02 US disclosed
US-6169208-B1 Process for producing a magnesium di[tetrakis(Faryl)borate] and products therefrom ALBEMARLE CORPORATION 2001-01-02 US disclosed