SCHEMBL716940

SCHEMBL716940

COc1c(F)c(F)[c]c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15757740 0.85 HSD17B10 (0.39) HSD17B10
SCHEMBL5364219 0.83
SCHEMBL6189654 0.79
SCHEMBL3763099 0.77 HSD17B10 (0.41) HSD17B10
SCHEMBL182607 0.74 HSD17B10 (0.40) HSD17B10
SCHEMBL4660966 0.73 HSD17B10 (0.35) HSD17B10
SCHEMBL1535908 0.71
SCHEMBL2353524 0.70 NQO1 (0.31)
SCHEMBL3702793 0.70
SCHEMBL17110568 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10253059-B2 Hybrid galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2019-04-09 US claimed
EP-3415522-A1 NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2018-12-19 EP claimed
US-9869931-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-16 US claimed
US-20170349622-A1 NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2017-12-07 US claimed
EP-3166956-A1 NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2017-05-17 EP claimed
EP-3129358-A1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES BASF SE (DE) 2017-02-15 EP claimed
US-20170029383-A1 Diaminotriazine Derivatives as Herbicides BASF SE (DE) 2017-02-02 US claimed
US-20160231652-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-11 US claimed
US-9243015-B2 Metallocorroles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-01-26 US claimed
WO-2016005311-A1 NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2016-01-14 WO claimed
US-6939963-B2 Method for the preparation of selectively-substituted corroles and new substituted corroles TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2005-09-06 US claimed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO claimed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US claimed
EP-1411927-A4 METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES TECHNION RES & DEV FOUNDATION (IL) 2005-04-20 EP claimed
US-20040180872-A1 Use as catalyst , in photovoltaic cells, drugs for diagnosis and photodynamic treatment of tumors or as chemical intermediates; metal complexes of 2,17-Bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2004-09-16 US claimed
EP-1411927-A1 METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES Technion Research and Development Foundation Ltd. (IL) 2004-04-28 EP claimed
WO-2003004021-A1 METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2003-01-16 WO claimed
EP-0281439-B1 ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES ROUSSEL-UCLAF (FR) 1991-06-12 EP claimed
EP-0378026-A1 Fluor derivatives of 3-ethenyl-2,2-dimethyl cyclopropane-carboxylic acid, method for their preparation, their use as pesticides and compositions containing them ROUSSEL-UCLAF (FR) 1990-07-18 EP claimed
EP-0281439-A1 Esters of cyclopropanecarboxylic acids related to pyrethric acid, process for their preparation and their use as parasiticides ROUSSEL-UCLAF (FR) 1988-09-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10253059-B2 Hybrid galactoside inhibitor of galectins LGALS1, LGALS3, LGALS2 HSD17B10 1833/4885
US-20170029383-A1 Diaminotriazine Derivatives as Herbicides DDT, CBR3, HDHD5 HSD17B10 1042/4885
US-20040180872-A1 Use as catalyst , in photovoltaic cells, drugs for diagnosis and photodynamic treatment of tumors or as chemical intermediates; metal complexes of 2,17-Bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole EPOR, NR2E3, CBR1 HSD17B10 748/4885
US-20170349622-A1 NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS LGALS1, LGALS3, LGALS2 HSD17B10 1770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.