Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600684 | 0.88 | CHRM1 (0.35) | KDM4EALDH1A1ALOX15POLBTP53 | |
| SCHEMBL600683 | 0.88 | CHRM1 (0.35) | KDM4EALDH1A1ALOX15POLBTP53 | |
| SCHEMBL601629 | 0.88 | CHRM1 (0.35) | KDM4EALDH1A1ALOX15POLBTP53 | |
| SCHEMBL600638 | 0.85 | TAAR1 (0.35) | KDM4EALDH1A1ALOX15POLBTP53 | |
| SCHEMBL600637 | 0.85 | TAAR1 (0.35) | KDM4EALDH1A1ALOX15POLBTP53 | |
| SCHEMBL601803 | 0.85 | TAAR1 (0.35) | KDM4EALDH1A1ALOX15POLBTP53 | |
| SCHEMBL1306189 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1ALOX15POLBMEN1 | |
| SCHEMBL4660815 | 0.83 | CHRM1 (0.32) | CHRM1BCHE | |
| SCHEMBL600511 | 0.83 | ACACB (0.32) | KDM4EALDH1A1MEN1KMT2ACHRM1 | |
| SCHEMBL602320 | 0.80 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004182-A1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007107565-A1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | WO | disclosed |