Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | CSF1R | P07333 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661493 | 0.84 | HTT (0.35) | POLBKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL4662703 | 0.82 | JAK2 (0.40) | MAPTSYK | |
| SCHEMBL4661242 | 0.82 | POLB (0.45) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL4343366 | 0.75 | KDM4E (0.48) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL4661441 | 0.74 | CDK4 (0.36) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4662731 | 0.73 | PTPN1 (0.34) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4661233 | 0.69 | HIF1A (0.40) | POLBKDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL4661367 | 0.69 | ACACB (0.42) | OPRM1OPRD1 | |
| SCHEMBL4661324 | 0.68 | PTPN1 (0.39) | POLBLMNAMEN1KMT2AMAPT | |
| SCHEMBL28339089 | 0.68 | TDP1 (0.45) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |