SCHEMBL4661473

SCHEMBL4661473

CO[Si](CCCNCC(C)C(=O)O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 1/20 0.33
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
FOLH1 Q04609 2/20 0.30
NAALAD2 Q9Y3Q0 2/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514943 0.97 APAF1 (0.31) APAF1
SCHEMBL23795579 0.86 MEN1 (0.30) MEN1KMT2A
SCHEMBL4662722 0.84 ALDH1A1 (0.33) APAF1
SCHEMBL17707055 0.84
SCHEMBL4443939 0.83 TSHR (0.30)
SCHEMBL11906115 0.81
SCHEMBL11905091 0.80
SCHEMBL2616721 0.80 HPGD (0.32)
SCHEMBL23795573 0.80 FOLH1 (0.33) MEN1KMT2AFOLH1
SCHEMBL11905861 0.79 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971656-B1 SILYLATED POLYURENTHANE-POLYUREA PROTECTIVE COATING COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2013-07-24 EP claimed
EP-1877452-B1 SCRATCH RESISTANT CURABLE COATING COMPOSITION SHERWIN WILLIAMS CO (US) 2008-12-24 EP claimed
EP-0082528-B1 SILANE CONTAINING ISOCYANATE TERMINATED POLYURETHANE POLYMERS UNION CARBIDE CORPORATION (US) 1986-04-30 EP disclosed