SCHEMBL4661512

SCHEMBL4661512

CC(C)Oc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.78
▸ LMNA P02545 5/20 0.78
▸ KMT2A Q03164 3/20 0.78
▸ ALDH1A1 P00352 2/20 0.78
▸ HPGD P15428 2/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ MAPK1 P28482 3/20 0.46
▸ HTT P42858 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ PGR P06401 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ SLC6A2 P23975 1/20 0.46
▸ PDE4A P27815 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ HRH1 P35367 1/20 0.46
▸ SLC6A3 Q01959 1/20 0.46
▸ PDE4D Q08499 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulisobenzone SCHEMBL167868 0.88 LMNA (1.00) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL16330 0.88 LMNA (1.00) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL9474717 0.88 LMNA (1.00) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL29360128 0.88 LMNA (1.00) MAPTLMNAKMT2AALDH1A1HPGD
SCHEMBL4662732 0.87 LMNA (0.71) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL11142507 0.86 LMNA (0.97) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL11277589 0.86 LMNA (0.97) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL10723301 0.86 LMNA (0.97) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL22712408 0.86 LMNA (0.97) MAPTLMNAKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL6295950 0.86 LMNA (0.97) MAPTLMNAKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427697-B1 SULPHONATION OF PHENOLS GREAT LAKES CHEMICAL EUROP (CH) 2008-12-24 — — EP disclosed
CN-1239477-C Sulphonation of phenols GREAT LAKES CHEMICAL EUROP (CH) 2006-02-01 — — CN disclosed
US-6936732-B2 Sulphonation of phenols ADDIVANT USA, LLC 2005-08-30 — — US disclosed
US-20050054876-A1 Sulphonation of phenols ADDIVANT USA, LLC 2005-03-10 — — US disclosed
CN-1556792-A Sulphonation of phenols �����ѧ��˾ŷ�޷ֹ�˾ 2004-12-22 — — CN disclosed
EP-1427697-A1 SULPHONATION OF PHENOLS Great Lakes Chemical (Europe) GmbH (CH) 2004-06-16 — — EP disclosed
WO-2003027063-A1 SULPHONATION OF PHENOLS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2003-04-03 — — WO disclosed
EP-0351615-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF Aktiengesellschaft (DE) 1992-10-28 — — EP disclosed
US-5072034-A PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 — — US disclosed
EP-0351615-A1 Process for the preparation of 4-alkoxy-2-hydroxybenzophenone-5-sulfonic acids BASF Aktiengesellschaft (DE) 1990-01-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054876-A1 Sulphonation of phenols CBR3, C1S, C1R MAPT 4859/4885LMNA 3440/4885KMT2A 3243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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