Sulisobenzone

Sulisobenzone

SCHEMBL6295950

COc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)O.[KH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.97
MAPT P10636 5/20 0.97
KMT2A Q03164 4/20 0.97
ALDH1A1 P00352 2/20 0.97
HPGD P15428 3/20 0.68
KDM4E B2RXH2 2/20 0.68
HSD17B10 Q99714 2/20 0.68
CYP3A4 P08684 1/20 0.68
RECQL P46063 1/20 0.68
MAPK1 P28482 2/20 0.52
HTT P42858 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C19 P33261 2/20 0.52
PGR P06401 1/20 0.52
SLC6A2 P23975 1/20 0.52
PDE4A P27815 1/20 0.52
HRH1 P35367 1/20 0.52
SLC6A3 Q01959 1/20 0.52
PDE4D Q08499 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulisobenzone SCHEMBL16330 0.99 LMNA (1.00) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL9474717 0.99 LMNA (1.00) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL167868 0.99 LMNA (1.00) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL29360128 0.99 LMNA (1.00) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL10723301 0.97 LMNA (0.97) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL545162 0.97 LMNA (0.97) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL22712408 0.97 LMNA (0.97) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL11142507 0.97 LMNA (0.97) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL489977 0.97 LMNA (0.97) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL10621764 0.97 MAPT (0.97) LMNAMAPTKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3496699-A1 N-METHYL-N-((2S,3R,4R,5R)-2,3,4,5,6-PENTAHYDROXYHEXYL)-(Z)-OCTADEC-9-ENAMIDE FOR REDUCTION OF EYE IRRITATION Werner & Mertz GmbH (DE) 2019-06-19 EP disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
US-6890881-B2 Thermal recording materials MITSUBISHI PAPER MILLS LTD. (JP) 2005-05-10 US disclosed
US-20040029056-A1 Thermal recording materials MITSUBISHI PAPER MILLS LTD. (JP) 2004-02-12 US disclosed
US-4864324-A INK JET RECORDING USING A METALLOPHTHALOCYANINE DYE CANON KABUSHIKI KAISHA (JP) 1989-09-05 US disclosed