Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.44 |
| ▸ | PI4KA | P42356 | 13/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 13/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 13/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580610 | 0.79 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4661802 | 0.78 | ADORA2A (0.65) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28413958 | 0.78 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28013019 | 0.76 | CYP1A2 (0.35) | — | |
| SCHEMBL28029278 | 0.76 | ADORA2A (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2558880 | 0.76 | PI4KA (0.44) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28410735 | 0.76 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL79000 | 0.75 | XDH (0.51) | — | |
| SCHEMBL27320524 | 0.74 | PI4KA (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6911224 | 0.74 | ADORA2A (0.41) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110430897-B | Conjugation unit and molecular construct comprising same | 免疫功坊股份有限公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-103525918-B | Primer, method and kit for detecting ER (estrogen receptor) beta gene intron 5 CA (cytosine adenine) repetitive sequence | CHANGSHA ADICON CLINICAL LAB INC | 2015-05-27 | — | — | CN | disclosed |
| CN-103525918-A | Primer, method and kit for detecting ER (estrogen receptor) beta gene intron 5 CA (cytosine adenine) repetitive sequence | CHANGSHA ADICON CLINICAL LAB CO LTD | 2014-01-22 | — | — | CN | disclosed |
| US-20110020333-A1 | Angiogenesis Pathway Gene Polymorphisms for Therapy Selection | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-01-27 | — | — | US | disclosed |
| US-7807364-B2 | Angiogenesis pathway gene polymorphisms for therapy selection | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-10-05 | — | — | US | disclosed |
| EP-1991268-A4 | ANGIOGENESIS PATHWAY GENE POLYMORPHISMS FOR THERAPY SELECTION | UNIV SOUTHERN CALIFORNIA (US) | 2009-08-26 | — | — | EP | disclosed |
| EP-1991268-A2 | ANGIOGENESIS PATHWAY GENE POLYMORPHISMS FOR THERAPY SELECTION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007103814-A2 | ANGIOGENESIS PATHWAY GENE POLYMORPHISMS FOR THERAPY SELECTION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070207486-A1 | determining whether a patient will respond to anti-VEGF antibody based chemotherapy by screening suitable cell or tissue sample from the patient for at least one genomic polymorphism or genotype; using a bevacizumab antibody or an antibody that binds to the same epitope on VEGF and and cyclophosphamide | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-09-06 | — | — | US | disclosed |
| EP-1005478-A1 | RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME | Pitsch, Stefan (CH) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999009044-A1 | RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME | PITSCH STEFAN (CH) | 1999-02-25 | — | — | WO | disclosed |
| US-5780607-A | PYRANOSYL NUCLEOSIDE MONOMER UNITS CONNECTED BY AMIDE LINKAGES | HOFFMANN-LA ROCHE INC. (US) | 1998-07-14 | — | — | US | disclosed |