Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660482 | 0.86 | DGAT1 (0.34) | NOS1NOS3NOS2DGAT1SLC7A5 | |
| SCHEMBL3080102 | 0.85 | MAPK1 (0.41) | MAPK1NOS1HRH2HRH1NOS3 | |
| SCHEMBL522783 | 0.85 | MAPK1 (0.41) | MAPK1NOS1HRH2HRH1NOS3 | |
| SCHEMBL522812 | 0.85 | MAPK1 (0.41) | MAPK1NOS1HRH2HRH1NOS3 | |
| Hydrochloric Acid SCHEMBL318950 | 0.83 | MAPK1 (0.40) | MAPK1NOS1HRH2HRH1NOS3 | |
| Hydrochloric Acid SCHEMBL522784 | 0.83 | MAPK1 (0.40) | MAPK1NOS1HRH2HRH1NOS3 | |
| Hydrochloric Acid SCHEMBL522782 | 0.83 | MAPK1 (0.40) | MAPK1NOS1HRH2HRH1NOS3 | |
| SCHEMBL5692825 | 0.81 | DGAT1 (0.32) | NOS1NOS3NOS2DGAT1SLC7A5 | |
| SCHEMBL20503360 | 0.81 | DGAT1 (0.32) | NOS1NOS3NOS2DGAT1SLC7A5 | |
| SCHEMBL6837920 | 0.80 | MEN1 (0.34) | NOS1NOS3NOS2DGAT1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004670-A1 | PROCESS FOR THE MANUFACTURE OF LYSOBACTIN DERIVATIVES | AiCuris GmbH & Co. KG (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007118693-A1 | PROCESS FOR THE MANUFACTURE OF LYSOBACTIN DERIVATIVES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |