Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661867 | 0.86 | MAPK1 (0.36) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL30227945 | 0.85 | NOS1 (0.36) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| Hydrochloric Acid SCHEMBL6435071 | 0.85 | NOS1 (0.36) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL12936767 | 0.85 | NOS1 (0.36) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL2735019 | 0.85 | NOS1 (0.36) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL5692825 | 0.81 | DGAT1 (0.32) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL20503360 | 0.81 | DGAT1 (0.32) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL4540621 | 0.80 | DGAT1 (0.31) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL6837920 | 0.80 | MEN1 (0.34) | DGAT1NOS1NOS3NOS2SLC7A5 | |
| SCHEMBL4727127 | 0.80 | PTGS1 (0.39) | DGAT1NOS1NOS3NOS2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876490-A1 | PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997027304-A9 | PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA | — | 1997-10-09 | — | — | WO | disclosed |
| WO-1997027304-A1 | PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-07-31 | — | — | WO | disclosed |