Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728018 | 0.80 | F2 (0.58) | KMT2AALDH1A1HPGDF2PRSS1 | |
| SCHEMBL3279948 | 0.75 | KMT2A (0.51) | KMT2AFBP1ALDH1A1F2PKM | |
| SCHEMBL30986723 | 0.74 | FBP1 (0.59) | KMT2AFBP1ALDH1A1HPGDHIF1A | |
| SCHEMBL6920157 | 0.74 | KMT2A (0.53) | KMT2AFBP1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL1706529 | 0.73 | POLB (0.46) | KMT2AFBP1HPGDHIF1APKM | |
| SCHEMBL1706722 | 0.73 | POLB (0.46) | KMT2AFBP1HPGDHIF1APKM | |
| SCHEMBL7509196 | 0.72 | GAA (0.65) | KMT2AFBP1ALDH1A1HPGDHCRTR2 | |
| SCHEMBL27596170 | 0.71 | KMT2A (0.44) | KMT2AFBP1ALDH1A1F2PKM | |
| SCHEMBL1706810 | 0.71 | KMT2A (0.55) | KMT2AFBP1ALDH1A1PKM | |
| SCHEMBL10984108 | 0.71 | F2 (0.46) | KMT2AALDH1A1HPGDF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003975-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |