Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047336 | 0.89 | CYP19A1 (0.76) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL20946439 | 0.87 | CYP19A1 (0.72) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL12813108 | 0.87 | CYP19A1 (0.76) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL5444156 | 0.87 | CYP19A1 (0.72) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL30504862 | 0.87 | CYP19A1 (0.72) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL9813024 | 0.86 | AKR1C3 (0.76) | ALDH1A1GAAPOLBMAPTAKR1C3 | |
| SCHEMBL5455007 | 0.86 | CYP19A1 (0.66) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL5130325 | 0.86 | AKR1C3 (0.79) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL26229835 | 0.85 | CYP19A1 (0.69) | CYP19A1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL21048461 | 0.84 | KEAP1 (0.81) | CYP19A1KEAP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820429-B | Novel compositions and methods for immunotherapy comprising small molecule integrin receptor-ligand agonist adjuvants | 7山药物有限责任公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-107820429-A | Include the new compositions and method for immunization therapy of small molecule integrin receptors ligand activator adjuvant | 7山利益有限责任公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-100548979-C | A kind of method of synthetic 3-methyl amino indole compound | SHANGHAI INST ORGANIC CHEM (CN) | 2009-10-14 | — | — | CN | disclosed |
| EP-2007760-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIZIN-3-ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007108569-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIZIN-3-ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-09-27 | — | — | WO | disclosed |
| CN-100999490-A | Process of synthesizing 3-methyl amino indole compound | SHANGHAI INST OF ORGANIST CHEM (CN) | 2007-07-18 | — | — | CN | disclosed |
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |