Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.72 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407414 | 0.90 | KEAP1 (1.00) | KEAP1CA12CA9LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3516799 | 0.88 | KEAP1 (0.96) | KEAP1CA12CA9LMNASMN1; SMN2 | |
| SCHEMBL4662824 | 0.88 | KEAP1 (0.69) | KEAP1CYP19A1CA12CA9LMNA | |
| SCHEMBL4662812 | 0.88 | CYP19A1 (0.71) | KEAP1CYP19A1CA12CA9LMNA | |
| SCHEMBL4661682 | 0.88 | CYP19A1 (0.71) | KEAP1CYP19A1CA12CA9LMNA | |
| SCHEMBL4661757 | 0.88 | CYP19A1 (0.71) | KEAP1CYP19A1CA12CA9LMNA | |
| SCHEMBL14025561 | 0.86 | KEAP1 (0.71) | KEAP1CYP19A1CA12CA9LMNA | |
| SCHEMBL1048486 | 0.85 | AKR1C3 (0.66) | KEAP1CYP19A1LMNASMN1; SMN2HDAC2 | |
| SCHEMBL13888909 | 0.84 | KEAP1 (0.63) | KEAP1CYP19A1CA12CA9LMNA | |
| SCHEMBL6567375 | 0.84 | CYP19A1 (0.74) | KEAP1CYP19A1CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417198-B1 | POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES | RHODIA OPERATIONS (FR) | 2019-06-12 | — | — | EP | claimed |
| EP-2417198-B1 | POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES | RHODIA OPERATIONS (FR) | 2019-06-12 | — | — | EP | disclosed |