Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL17492265 | 1.00 | CA1 (0.59) | CA1CA9TP53ALDH1A1LMNA | |
| Lactic Acid SCHEMBL28013571 | 0.93 | CA1 (0.52) | CA1CA9TP53ALDH1A1LMNA | |
| Lactic Acid SCHEMBL27514349 | 0.92 | CA1 (0.52) | CA1CA9TP53ALDH1A1LMNA | |
| Lactic Acid SCHEMBL6903560 | 0.92 | CA1 (0.52) | CA1CA9TP53ALDH1A1LMNA | |
| Lactic Acid SCHEMBL5570421 | 0.92 | CA1 (0.50) | CA1CA9TP53ALDH1A1LMNA | |
| Acetic Acid SCHEMBL27560595 | 0.84 | CA1 (0.70) | CA1CA9TP53ALDH1A1LMNA | |
| Bicarbonate SCHEMBL8606312 | 0.84 | CA1 (0.76) | CA1CA9TP53ALDH1A1LMNA | |
| Hydrogen Peroxide SCHEMBL27660851 | 0.84 | CA1 (0.84) | CA1CA9TP53ALDH1A1LMNA | |
| SCHEMBL18237435 | 0.83 | CA1 (0.52) | CA1CA9TP53ALDH1A1LMNA | |
| Butyrolactone SCHEMBL16395005 | 0.82 | CA1 (0.54) | CA1CA9TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4360834-A2 | METHOD FOR MANUFACTURING A CLOSURE FOR A PRODUCT-RETAINING CONTAINER | Vinventions USA, LLC (US) | 2024-05-01 | — | — | EP | claimed |
| CN-112805225-B | Decorative closure for container | 唯万盛美国有限责任公司 | 2024-01-16 | — | — | CN | claimed |
| CN-111000661-B | Composite artificial blood vessel and preparation method thereof | 上海畅迪医疗科技有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-111315564-B | Method for producing a closure for a product-retaining container | 唯万盛美国有限责任公司 | 2023-04-04 | — | — | CN | claimed |
| CN-114395930-A | Direct injection type reactive dye ink used for printed fabric and free of front and back treatment and application thereof | 山东中康国创先进印染技术研究院有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-111068113-B | Nanofiber coating artificial blood vessel, and preparation method and preparation device of coating | 上海畅迪医疗科技有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-112805225-A | Decorative closure for container | 唯万盛美国有限责任公司 | 2021-05-14 | — | — | CN | claimed |
| CN-111315660-A | Method for producing a closure for a product-retaining container | 唯万盛美国有限责任公司 | 2020-06-19 | — | — | CN | claimed |
| CN-111315564-A | Method for producing a closure for a product-retaining container | 唯万盛美国有限责任公司 | 2020-06-19 | — | — | CN | claimed |
| US-20200029557-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2020-01-30 | — | — | US | claimed |
| EP-3519376-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | Commonwealth Scientific and Industrial Research Organisation (AU) | 2019-08-07 | — | — | EP | claimed |
| CN-109952283-A | Control release agrochemical compositions | 联邦科学与工业研究组织 | 2019-06-28 | — | — | CN | claimed |
| CN-108852449-A | A kind of vascular occlusion device and hemostatic system | 上海纽脉太惟医疗科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| WO-2018058193-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-04-05 | — | — | WO | claimed |
| CN-104640904-B | Biodegradable polymer compound | 郡是株式会社 | 2017-05-24 | — | — | CN | claimed |
| CN-104841013-A | Composite nanofiber/nano yarn double-layer intravascular stent and preparation method thereof | NAT UNIV DONG HWA | 2015-08-19 | — | — | CN | claimed |
| CN-104640904-A | Biodegradable polymer compound | GUNZE CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-103266421-B | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2014-07-02 | — | — | CN | claimed |
| CN-103266421-A | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2013-08-28 | — | — | CN | claimed |
| US-11981842-B2 | Tackifier for lactic acid based hot-melt adhesive | PURAC BIOCHEM B.V. (NL) | 2024-05-14 | — | — | US | disclosed |
| CN-117797308-A | Hydrogel dressing based on hydroformylation hyaluronic acid and antibacterial heptapeptide and preparation method thereof | 浙江大学绍兴研究院 | 2024-04-02 | — | — | CN | disclosed |
| CN-107550611-B | Vascular stent | 科塞尔医疗科技（苏州）有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-220459458-U | Vascular stent | 苏州天鸿盛捷医疗器械有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-112805225-B | Decorative closure for container | 唯万盛美国有限责任公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-111000661-B | Composite artificial blood vessel and preparation method thereof | 上海畅迪医疗科技有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-111000660-B | 3D printing artificial blood vessel and preparation method thereof | 上海畅迪医疗科技有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116785038-A | Support frame | 正林康宏 | 2023-09-22 | — | — | CN | disclosed |
| CN-113557282-B | Tackifier for lactic acid-based hot melt adhesives | 普拉克生化公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116590828-A | Preparation method of low-permeability woven artificial blood vessel | 武汉纺织大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-219230280-U | Vascular stent | 苏州天鸿盛捷医疗器械有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-3466359-B1 | IMPLANTABLE FILMS FOR DRUG RELEASE | DEPUY SYNTHES PRODUCTS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-219126904-U | Multistage type ball expands tectorial membrane bracket system | 江苏百优达生命科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116115399-A | Multistage type ball expands tectorial membrane bracket system | 江苏百优达生命科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112842618-B | Small-caliber degradable composite artificial blood vessel and preparation method thereof | 北京理工大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-116036026-A | Water-soluble salt microsphere and preparation method thereof | 重庆电子工程职业学院 | 2023-05-02 | — | — | CN | disclosed |
| CN-111315564-B | Method for producing a closure for a product-retaining container | 唯万盛美国有限责任公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-111511736-B | Nitrogen-containing 6-membered ring compound | 旭化成制药株式会社 | 2023-03-24 | — | — | CN | disclosed |
| CN-115581539-A | Biodegradable full-lamination anti-displacement esophageal stent for preventing esophageal stenosis after ESD (electro-static discharge) operation | 西安交通大学第一附属医院 | 2023-01-10 | — | — | CN | disclosed |
| CN-113181433-B | Vascularization promoting three-dimensional nanofiber tubular stent and preparation method thereof | 嘉兴学院 | 2022-05-20 | — | — | CN | disclosed |
| CN-114395930-A | Direct injection type reactive dye ink used for printed fabric and free of front and back treatment and application thereof | 山东中康国创先进印染技术研究院有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114364351-A | Support frame | 正林康宏 | 2022-04-15 | — | — | CN | disclosed |
| CN-111068113-B | Nanofiber coating artificial blood vessel, and preparation method and preparation device of coating | 上海畅迪医疗科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111068113-B | Nanofiber coating artificial blood vessel, and preparation method and preparation device of coating | 上海畅迪医疗科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114059362-A | Thermosensitive gelation direct injection type textile ink and application thereof | 江苏博来特新材料有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113677373-A | RNAi molecules | 日东电工株式会社 | 2021-11-19 | — | — | CN | disclosed |
| US-20210348035-A1 | TACKIFIER FOR LACTIC ACID BASED HOT-MELT ADHESIVE | PURAC BIOCHEM B.V. (NL) | 2021-11-11 | — | — | US | disclosed |
| EP-3898868-A1 | TACKIFIER FOR LACTIC ACID BASED HOT-MELT ADHESIVE | Purac Biochem B.V. (NL) | 2021-10-27 | — | — | EP | disclosed |
| CN-113557282-A | Tackifier for lactic acid-based hot melt adhesive | 普拉克生化公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113181433-A | Vascularization promoting three-dimensional nanofiber tubular stent and preparation method thereof | 嘉兴学院 | 2021-07-30 | — | — | CN | disclosed |
| CN-113038956-A | RNAi molecules for cancer treatment | 日东电工株式会社 | 2021-06-25 | — | — | CN | disclosed |
| CN-112842618-A | Degradable composite artificial blood vessel and preparation method and application thereof | 北京理工大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-112805225-A | Decorative closure for container | 唯万盛美国有限责任公司 | 2021-05-14 | — | — | CN | disclosed |
| WO-2020196913-A1 | STENT | 株式会社ジェイ・エム・エス | 2020-10-01 | — | — | WO | disclosed |
| US-20200222335-A1 | Films and Methods of Manufacture | SYNTHES USA, LLC | 2020-07-16 | — | — | US | disclosed |
| WO-2020127521-A1 | TACKIFIER FOR LACTIC ACID BASED HOT-MELT ADHESIVE | PURAC BIOCHEM B.V. (NL) | 2020-06-25 | — | — | WO | disclosed |
| CN-111315660-A | Method for producing a closure for a product-retaining container | 唯万盛美国有限责任公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111315564-A | Method for producing a closure for a product-retaining container | 唯万盛美国有限责任公司 | 2020-06-19 | — | — | CN | disclosed |
| US-10617653-B2 | Films and methods of manufacture | DePuy Synthes Products, Inc. (US) | 2020-04-14 | — | — | US | disclosed |
| US-20200029557-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2020-01-30 | — | — | US | disclosed |
| US-20200031728-A1 | CONTROLLED RELEASE GRANULAR FERTILISER | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2020-01-30 | — | — | US | disclosed |
| CN-110478521-A | Medicament-carrying nano-fiber and its preparation method and application | UNIV GUILIN MEDICAL | 2019-11-22 | — | — | CN | disclosed |
| EP-3519376-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | Commonwealth Scientific and Industrial Research Organisation (AU) | 2019-08-07 | — | — | EP | disclosed |
| EP-3519375-A1 | CONTROLLED RELEASE GRANULAR FERTILISER | Commonwealth Scientific and Industrial Research Organisation (AU) | 2019-08-07 | — | — | EP | disclosed |
| CN-106178120-B | A kind of composite material intravascular stent and preparation method thereof of bionical native blood vessels three-decker | 东华大学 | 2019-05-03 | — | — | CN | disclosed |
| EP-3466359-A1 | IMPLANTABLE FILMS FOR DRUG RELEASE | DePuy Synthes Products, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| CN-109476144-A | Biodegradable film | 诺瓦蒙特股份公司 | 2019-03-15 | — | — | CN | disclosed |
| EP-2797530-B1 | FILMS AND METHODS OF MANUFACTURE | DEPUY SYNTHES PRODUCTS INC (US) | 2018-09-26 | — | — | EP | disclosed |
| CN-105451785-B | Bone-regeneration material kit, paste bone-regeneration material, bone-regeneration material and bone grafting material | 郡是株式会社 | 2018-07-17 | — | — | CN | disclosed |
| WO-2018058194-A1 | CONTROLLED RELEASE GRANULAR FERTILISER | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-04-05 | — | — | WO | disclosed |
| WO-2018058193-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-04-05 | — | — | WO | disclosed |
| CN-206450657-U | A kind of artificial blood vessel's vivo environment analogue means | 南通纺织丝绸产业技术研究院 | 2017-08-29 | — | — | CN | disclosed |
| CN-104640904-B | Biodegradable polymer compound | 郡是株式会社 | 2017-05-24 | — | — | CN | disclosed |
| CN-106596866-A | Artificial blood vessel in-vivo environment simulation apparatus | 南通纺织丝绸产业技术研究院 | 2017-04-26 | — | — | CN | disclosed |
| CN-104862823-B | Preparation method for PDEGMA (poly diethylene glycol dimethacrylate) with P(LLA-CL) (lactic acid caprolactone copolymer) electrostatic spinning temperature-sensitive nanofiber | 东华大学 | 2017-01-18 | — | — | CN | disclosed |
| CN-106178120-A | A kind of composite intravascular stent of bionical native blood vessels three-decker and preparation method thereof | 东华大学 | 2016-12-07 | — | — | CN | disclosed |
| US-20160287527-A1 | Films And Methods Of Manufacture | SYNTHES USA, LLC | 2016-10-06 | — | — | US | disclosed |
| US-9381683-B2 | Films and methods of manufacture | DePuy Synthes Products, Inc. (US) | 2016-07-05 | — | — | US | disclosed |
| CN-104841013-A | Composite nanofiber/nano yarn double-layer intravascular stent and preparation method thereof | NAT UNIV DONG HWA | 2015-08-19 | — | — | CN | disclosed |
| CN-104841013-A | Composite nanofiber/nano yarn double-layer intravascular stent and preparation method thereof | NAT UNIV DONG HWA | 2015-08-19 | — | — | CN | disclosed |
| CN-104640904-A | Biodegradable polymer compound | GUNZE CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-104287869-A | Novel nanofiber membrane and yarn support for trachea transplantation and method for manufacturing novel nanofiber membrane and yarn support | SHANGHAI PULMONARY HOSPITAL | 2015-01-21 | — | — | CN | disclosed |
| CN-204106256-U | A kind of fibrous membrane/yarn count frame of the novel nano for graft of trachea | SHANGHAI PULMONARY HOSPITAL | 2015-01-21 | — | — | CN | disclosed |
| EP-2797530-A1 | FILMS AND METHODS OF MANUFACTURE | DePuy Synthes Products, LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| CN-103266421-B | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2014-07-02 | — | — | CN | disclosed |
| CN-103266421-B | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2014-07-02 | — | — | CN | disclosed |
| CN-103266421-B | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2014-07-02 | — | — | CN | disclosed |
| CN-103266421-A | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2013-08-28 | — | — | CN | disclosed |
| CN-103266421-A | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2013-08-28 | — | — | CN | disclosed |
| CN-103266421-A | Preparation method of caprolactone lactate copolymer/collagen/chitosan small-caliber intravascular stent | UNIV DONGHUA | 2013-08-28 | — | — | CN | disclosed |
| US-20130171410-A1 | FILMS AND METHODS OF MANUFACTURE | SYNTHES USA, LLC (US) | 2013-07-04 | — | — | US | disclosed |
| WO-2013101867-A1 | FILMS AND METHODS OF MANUFACTURE | DEPUTY SYNTHES PRODUCTS, LLC (US) | 2013-07-04 | — | — | WO | disclosed |
| CN-102813566-A | Coronary stent | FENG HAIQUAN | 2012-12-12 | — | — | CN | disclosed |
| CN-202568545-U | Coronary stent | UNIV INNER MONGOLIA TECHNOLOGY | 2012-12-05 | — | — | CN | disclosed |
| CN-101137700-B | Microparticle and pharmaceutical composition | TORAY INDUSTRIES | 2012-07-18 | — | — | CN | disclosed |
| CN-102497838-A | Support frame | JAPAN STENT TECHNOLOGY CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101133037-B | Six-membered heterocyclic compound and use thereof | ASAHI KASEI PHARMA CORP | 2012-05-09 | — | — | CN | disclosed |
| CN-102368977-A | Stent for tubular organs in vivo | UNIV KEIO | 2012-03-07 | — | — | CN | disclosed |
| EP-1581181-B1 | CONTROLLED RELEASE DEPOT FORMULATIONS | ALZA CORP (US) | 2008-12-24 | — | — | EP | disclosed |
| CN-101133037-A | Six-membered heterocyclic compound and use thereof | ASAHI KASEI PHARMA CORP (JP) | 2008-02-27 | — | — | CN | disclosed |
| EP-1857489-A1 | MICROPARTICLE AND PHARMACEUTICAL COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2007-11-21 | — | — | EP | disclosed |
| CN-1321094-A | Bone repair materials/artificial bone compositions | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-07 | — | — | CN | disclosed |
| EP-1120122-A1 | BONE REPAIR MATERIALS/ARTIFICIAL BONE COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |
| CN-1187122-A | Osteogenetic promoting pharmaceutial composition | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-08 | — | — | CN | disclosed |
| CN-1187122-A | Osteogenetic promoting pharmaceutial composition | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200029557-A1 | CONTROLLED RELEASE AGRICHEMICAL COMPOSITION | LGMN, IDUA, HNRNPU | CA1 66/4885CA9 1135/4885TP53 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.