Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635315 | 0.76 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL1635827 | 0.70 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL4660497 | 0.69 | — | — | |
| SCHEMBL4662019 | 0.64 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL1633796 | 0.64 | MAPT (0.35) | — | |
| SCHEMBL12096020 | 0.63 | MEN1 (0.39) | — | |
| SCHEMBL4661895 | 0.63 | — | — | |
| SCHEMBL8979662 | 0.61 | — | — | |
| SCHEMBL9704318 | 0.61 | — | — | |
| SCHEMBL4661991 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558230-B1 | SPIROCYCLOPROPYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | claimed |