Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634022 | 0.76 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL24587095 | 0.71 | ALOX5AP (0.31) | HSD11B1 | |
| SCHEMBL29642292 | 0.67 | — | — | |
| SCHEMBL1634321 | 0.67 | KMT2A (0.36) | HSD11B1 | |
| SCHEMBL11036084 | 0.66 | HSD11B1 (0.30) | HSD11B1 | |
| SCHEMBL25509617 | 0.66 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL906629 | 0.66 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL2761577 | 0.65 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL4662031 | 0.64 | LMNA (0.35) | — | |
| SCHEMBL4663140 | 0.64 | HSD11B1 (0.31) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558230-B1 | SPIROCYCLOPROPYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | claimed |